Su Miancheng, Dai Mei, Lü Xiaoying, Li Hongkun, Liu Jilin
National Engineering Research Center for Mordernization of TCM, Zhuhai 519020.
Zhong Yao Cai. 2002 May;25(5):339-42.
To investigate the inhibiting effect of Aining on the human gastric cancer cells.
Morphological and MTT methods were adopted to explore the inhibiting effect of Aining and cisplatin (DDP) on the proliferation of SGC-7901 cancer cell.
Apoptotic morphological changes were seen after the cells cultured with Aining and DDP; inhibiting rate of 1 g/L Aining group was 51%, which had no significant differences with the inhibiting rate 53% of the 25 mg/L DDP group. But both the Aining and the DDP groups were significantly different from the blank group (P < 0.01).
Not only DDP but also Aining could inhibit the proliferation activity of the human gastric cancer cells, and the traditional Chinese medicine compound prescription Aining is very likely to become a new medicine which is utilized to inhibit cancer.
探讨艾宁对人胃癌细胞的抑制作用。
采用形态学和MTT法，研究艾宁和顺铂（DDP）对SGC - 7901癌细胞增殖的抑制作用。
用艾宁和DDP培养细胞后可见凋亡形态学改变；1 g/L艾宁组的抑制率为51%，与25 mg/L DDP组53%的抑制率无显著差异。但艾宁组和DDP组与空白组均有显著差异（P < 0.01）。
DDP和艾宁均可抑制人胃癌细胞的增殖活性，中药复方制剂艾宁很有可能成为一种新的抗癌药物。
