Benoist S, Panis Y, Beaufour A, Bouhnik Y, Matuchansky C, Valleur P
Department of Surgery, Lariboisière Hospital, 2, Rue Ambroise Paré, 75475 Paris, Cedex 10, France.
Surg Endosc. 2003 May;17(5):814-8. doi: 10.1007/s00464-002-9103-4. Epub 2003 Jan 18.
Despite some encouraging preliminary results, the role of laparosropic surgery in the treatment of Crohn's disease (CD) is a subject of controversy and still under evaluation. The aim of this case-matched study was to compare the postoperative course of laparoscopic and open ileocecal resection in patients with CD in order to define the potential role of laparoscopic surgery in CD.
From 1998 to 2001, 24 consecutive patients with isolated Crohn's terminal ileitis treated by laparoscopic ileocecal resection (laparoscopy group) were compared with 32 patients matched for age, gender, duration of disease, preoperative steroid treatment, fistulizing disease, and associated surgical procedure, and treated by open resection (open group).
In the laparoscopy group, four procedures (17%) were converted. There were no deaths. The morbidity rate was 20% in the laparoscopy group and 10% in the open group (NS). There was no significant difference between the two groups in operating time, size of bowel resection and resection margin, postoperative morphine requirement, resumption of intestinal function, tolerance of solid diet, or length of hospital stay.
Laparoscopic ileocecal resection in CD is safe and effective, even for fistulizing disease. There are no significant differences between laparoscopic and open ileocecal resection, especially in terms of the mortality and mortality rates. Consequently, because laparoscopic surgery seems to offer cosmetic advantages, it should be considered the procedure of choice for patients with ileocecal CD.
尽管有一些令人鼓舞的初步结果,但腹腔镜手术在克罗恩病(CD)治疗中的作用仍存在争议,仍在评估中。本病例对照研究的目的是比较CD患者腹腔镜和开腹回盲部切除术的术后过程,以确定腹腔镜手术在CD中的潜在作用。
从1998年至2001年,将24例连续接受腹腔镜回盲部切除术治疗的孤立性克罗恩末端回肠炎患者(腹腔镜组)与32例年龄、性别、病程、术前类固醇治疗、瘘管病及相关手术操作相匹配并接受开腹切除术的患者(开腹组)进行比较。
腹腔镜组有4例手术(17%)中转开腹。无死亡病例。腹腔镜组的发病率为20%,开腹组为10%(无统计学差异)。两组在手术时间、肠切除范围和切缘、术后吗啡需求量、肠功能恢复、固体饮食耐受性或住院时间方面无显著差异。
CD患者的腹腔镜回盲部切除术是安全有效的,即使对于有瘘管病的患者也是如此。腹腔镜和开腹回盲部切除术之间无显著差异,尤其是在死亡率和发病率方面。因此,由于腹腔镜手术似乎具有美容优势,对于回盲部CD患者应将其视为首选手术方式。