Grillner Sten, Wallén Peter
Department of Neuroscience, The Retzius Laboratory Karolinska Institutet, SE-17177, Stockholm, Sweden.
Brain Res Brain Res Rev. 2002 Oct;40(1-3):92-106. doi: 10.1016/s0165-0173(02)00193-5.
The isolated brainstem-spinal cord of the lamprey is used as an experimental model in the analysis of the cellular bases of vertebrate locomotor behaviour. In this article we review the neural mechanisms involved in the control of steering, intersegmental co-ordination, as well as the segmental burst generation and the sensory contribution to motor pattern generation. Within these four components of the control system for locomotion, we now have good knowledge of not only the neurones that take part and their synaptic interactions, but also the membrane properties of these neurones, including ion channel subtypes, and their contribution to motor pattern generation.
七鳃鳗的离体脑干脊髓被用作分析脊椎动物运动行为细胞基础的实验模型。在本文中，我们回顾了参与控制转向、节间协调、节段性爆发产生以及感觉对运动模式产生的贡献的神经机制。在运动控制系统的这四个组成部分中，我们现在不仅对参与其中的神经元及其突触相互作用有了很好的了解，而且对这些神经元的膜特性，包括离子通道亚型，以及它们对运动模式产生的贡献也有了很好的了解。
