Guelmann Marcio, Britto Leandro R, Katz Joseph
Department of Pediatric Dentistry, University of Florida, Gainesville, FL 32610-0426, USA.
J Clin Pediatr Dent. 2003 Winter;27(2):123-6. doi: 10.17796/jcpd.27.2.v70187716x08286q.
A case of a 10 year-old boy with gingival overgrowth due to cyclosporin therapy after heart transplantation is described. Different treatment approaches are discussed and the surgical effect of CO2 laser is illustrated. The critical role of routine professional cleaning and good oral health maintenance for the healthy status of the gingival tissue is also emphasized in this paper. Replacement of cyclosporin by tacrolimus, another immunosuppressive agent associated with minimal to none gingival overgrowth, might be considered in cases with reported recurrences.
本文描述了一例10岁男孩在心脏移植后因环孢素治疗导致牙龈增生的病例。讨论了不同的治疗方法,并阐述了二氧化碳激光的手术效果。本文还强调了常规专业清洁和保持良好口腔卫生对牙龈组织健康状况的关键作用。对于报告有复发情况的病例,可考虑用他克莫司替代环孢素,他克莫司是另一种与牙龈增生极少或无关联的免疫抑制剂。