Darbar U R, Hopper C, Speight P M, Newman H N
Department of Periodontology, Eastman Dental Institute & Hospital, London, UK.
J Clin Periodontol. 1996 Oct;23(10):941-4. doi: 10.1111/j.1600-051x.1996.tb00515.x.
A case of severe gingival overgrowth associated with combined drug therapy of cyclosporin A and nifedipine is reported. The frequently increased vascularity of the gingival tissues in such cases often causes problems with bleeding both during and after surgery. Acrylic suckdown splints have been used postoperatively to assist haemostasis; however, these can interfere with function and cause discomfort. This report describes a combined treatment approach using conventional gingivectomy and carbon dioxide laser for the removal of the hypertrophic soft tissue. The benefits of such combined treatment include reduced bleeding during surgery with consequent reduced operating time and rapid post-operative haemostasis, thus eliminating the need for a splint.
报告了一例与环孢素A和硝苯地平联合药物治疗相关的严重牙龈过度生长病例。在此类病例中，牙龈组织血管频繁增多常导致手术期间及术后出血问题。术后曾使用丙烯酸吸除夹板辅助止血；然而，这些夹板会干扰功能并引起不适。本报告描述了一种联合治疗方法，即使用传统牙龈切除术和二氧化碳激光去除增生的软组织。这种联合治疗的益处包括手术期间出血减少，从而缩短手术时间，以及术后快速止血，因此无需使用夹板。
