Takeuchi Hideya, Kawano Toyokazu, Toda Tomohiro, Minamisono Yoshikazu, Nagasaki Susumu, Yao Takashi, Sugimachi Keizo
Institute of Gastroenterology of Hofu 14-33 Eki-minami, Hofu, Yamagichi 747, Japan.
Hepatogastroenterology. 2003 Jan-Feb;50(49):275-7.
We treated a 77-year-old Japanese man with cutaneous metastases from pancreatic adenocarcinoma. Physical examinations revealed reddish, non-tender and firm nodules in left axilla. Laboratory examination showed a remarkable elevation in the tumor markers of CA 19-9, DUPAN-2 and SPAN-1. Abdominal computed tomography showed a low-density mass in the tail of the pancreas, and histological examination of nodule in the axilla revealed a metastatic adenocarcinoma. The immunohistochemistry of CA 19-9 in the excised nodule was positive. Cutaneous metastasis from pancreatic adenocarcinoma is usually rare, and the prognosis is poor, as the disease is usually advanced.
我们治疗了一名患有胰腺腺癌皮肤转移的77岁日本男性。体格检查发现左腋窝有红色、无压痛的坚实结节。实验室检查显示CA 19-9、DUPAN-2和SPAN-1等肿瘤标志物显著升高。腹部计算机断层扫描显示胰腺尾部有一个低密度肿块，腋窝结节的组织学检查显示为转移性腺癌。切除结节中CA 19-9的免疫组织化学检查呈阳性。胰腺腺癌的皮肤转移通常很少见，且由于疾病通常已进展，预后较差。
