Unno R, Yamamoto Y
Jpn J Antibiot. 1976 Jan;29(1):11-6.
Seventeen cases of acute simple cystitis were treated by oral administration of amoxicillin at a daily dose of 1.0 g (250 mg X 4 in a day) for consecutive 7 days, and the following results were obtained. 1. Amoxicillin was remarkably effective in 11 of total 17 cases, effective in 2, slightly effective in 2 and non-effective in 2. 2. In terms of effect against isolated bacteria, amoxicillin was remarkably effective against 6 of 11 strains of E. coli, effective against 2, slightly effective against 2 and non-effective against 1, remarkably effective against 2 of 3 strains of Proteus mirabilis and non-effective against 1, and remarkably effective against one strain of Staphylococcus epidermidis. 3. There was no severe side effect specially to be mentioned.
17例急性单纯性膀胱炎患者口服阿莫西林进行治疗,每日剂量为1.0克(一日4次,每次250毫克),连续服用7天,获得以下结果。1. 在17例患者中,11例阿莫西林疗效显著,2例有效,2例稍有疗效,2例无效。2. 就对分离出的细菌的疗效而言,阿莫西林对11株大肠杆菌中的6株疗效显著,对2株有效,对2株稍有疗效,对1株无效;对3株奇异变形杆菌中的2株疗效显著,对1株无效;对1株表皮葡萄球菌疗效显著。3. 未出现特别值得提及的严重副作用。