Robson Martin C
Department of Surgery, University of South Florida, Tampa, FL 33620, USA.
Clin Plast Surg. 2003 Jan;30(1):57-65. doi: 10.1016/s0094-1298(02)00073-1.
Most individuals expect that healing is an inevitable outcome; wound healing is taken for granted. Although wound healing is perceived as inevitable, it can be fraught with problems and altered at many points. In the past, optimization of wound healing focused on minimizing contamination, accurate tissue approximation, and providing protection. With the advent of recombinant technology, optimization can now include manipulation of the molecular and cellular wound environment. Although the exact manipulative scheme has not yet evolved, it is clear from the multiple attempts reported in this article that understanding and progress is being made.
大多数人认为愈合是不可避免的结果;伤口愈合被视为理所当然。尽管伤口愈合被认为是不可避免的,但它可能充满问题并在许多环节发生改变。过去,伤口愈合的优化重点在于尽量减少污染、精确的组织对合以及提供保护。随着重组技术的出现,现在的优化可以包括对分子和细胞伤口环境的操控。尽管确切的操控方案尚未形成,但从本文报道的多次尝试中可以明显看出,正在取得理解和进展。