Tanasescu M, Hu F B
Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA.
Curr Diab Rep. 2001 Oct;1(2):187-91. doi: 10.1007/s11892-001-0032-8.
The epidemiologic evidence on the association between moderate alcohol intake and risk of coronary heart disease (CHD), biological mechanisms for this association, and potential hazards of alcohol intake in individuals with type 2 diabetes is reviewed here. Three prospective cohort studies have examined the association between alcohol consumption and risk of CHD among diabetics. The results indicated significant risk reductions, ranging from 34% to 79%, associated with light to moderate alcohol intake. Potential mechanisms include increased high-density lipoprotein cholesterol, decreased coagulation, and enhanced insulin sensitivity. Alcohol intake is also associated with certain risks among diabetics. However, for moderate alcohol consumption, the benefits would likely outweigh the risks.
本文综述了关于适度饮酒与冠心病（CHD）风险之间关联的流行病学证据、这种关联的生物学机制以及2型糖尿病患者饮酒的潜在危害。三项前瞻性队列研究考察了糖尿病患者饮酒与CHD风险之间的关联。结果表明，与轻度至适度饮酒相关的风险显著降低，幅度在34%至79%之间。潜在机制包括高密度脂蛋白胆固醇增加、凝血减少以及胰岛素敏感性增强。饮酒在糖尿病患者中也与某些风险相关。然而，对于适度饮酒而言，益处可能超过风险。
