Pattillo R A, Shalaby M R, Hussa R O, Bahl O P, Mattingly R F
Obstet Gynecol. 1976 May;47(5):557-61.
Crude APL hCG completely inhibited blastogenesis induced by phytohemagglutinin, pokeweed mitogen, or concanavalin A in normal lymphocytes and lymphocytes obtained from cancer patients. Phenol in quantities comparable to its concentration in commercial lyophilized APL hCG also completely inhibited all three mitogenic responses. By contrast, similar doses of highly purified hCG had no inhibitory effect; higher concentrations produced only slight inhibition. Beta-hCG had a partial (less than 50%) inhibitory effect that was dose-independent and nonreproducible.
粗制的急性早幼粒细胞白血病（APL）人绒毛膜促性腺激素（hCG）完全抑制了植物血凝素、商陆有丝分裂原或刀豆球蛋白A在正常淋巴细胞以及从癌症患者获取的淋巴细胞中诱导的细胞增殖。与商业冻干APL hCG中其浓度相当的酚量也完全抑制了所有这三种有丝分裂反应。相比之下，相似剂量的高度纯化hCG没有抑制作用；更高浓度仅产生轻微抑制。β-hCG具有部分（小于50%）抑制作用，该作用与剂量无关且不可重复。
