Sarkar A, Sengupta R, Krzywinski J, Wang X, Roth C, Collins F H
Center for Tropical Disease Research and Training, Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556-0369, USA.
Insect Biochem Mol Biol. 2003 Apr;33(4):381-7. doi: 10.1016/s0965-1748(03)00004-3.
We report the identification of genomic sequences in various anopheline mosquitoes (family Culicidae: suborder Nematocera: order Diptera) showing homology to the class II, short inverted-terminal-repeat (ITR) transposable element P from Drosophila melanogaster (family Drosophilidae; suborder Brachycera: order Diptera). Anopheles gambiae appears to have at least six distinct P elements. Other anopheline species, including four additional members of the An. gambiae species complex (An. arabiensis, An. merus, An. melas and An. quadriannulatus), Anopheles stephensi (all subgenus Cellia), An. quadrimaculatus (subgenus Anopheles) and Anopheles albimanus (subgenus Nyssorhynchus) also possess P elements similar to those found in An. gambiae. Ten distinct P element types were identified in the genus Anopheles. At least two of the An. gambiae elements appears to be intact and potentially functional. Phylogenetic analysis of the anopheline P elements reveals them to belong to a distinctly different clade from the brachyceran P elements.
我们报告了在各种按蚊（蚊科：长角亚目：双翅目）中鉴定出的基因组序列，这些序列与黑腹果蝇（果蝇科；短角亚目：双翅目）的II类短反向末端重复（ITR）转座元件P具有同源性。冈比亚按蚊似乎至少有六个不同的P元件。其他按蚊物种，包括冈比亚按蚊物种复合体的另外四个成员（阿拉伯按蚊、梅氏按蚊、黑足按蚊和四带按蚊）、斯氏按蚊（均为塞利娅亚属）、四斑按蚊（按蚊亚属）和白跗按蚊（尼氏按蚊亚属）也拥有与冈比亚按蚊中发现的类似的P元件。在按蚊属中鉴定出了十种不同的P元件类型。冈比亚按蚊的至少两个元件似乎是完整的且可能具有功能。对按蚊P元件的系统发育分析表明，它们属于与短角类P元件明显不同的进化枝。
