Lundgren D W, Farrell P M, Cohen L F, Hankins J
Proc Soc Exp Biol Med. 1976 May;152(1):81-5. doi: 10.3181/00379727-152-39333.
Perchloric acid-extractable whole blood spermidine and spermine concentrations were determined over a 4-week period in three men, four women, and one ovariectomized woman. Individual male spermidine/spermine ratios showed little fluctuation and similar values were obtained for each of the three males studied. Male spermidine and spermine concentrations, although stable for each male, varied from one subject to the next. Individual female spermidine/spermine ratios, as well as individual concentrations, fluctuated substantially when compared to those valued obtained for males; female ratios appear to rise and fall as a function of the menstrual cycle. The spermidine/spermine ratios obtained from a normal female receiving oral contraceptive, as well as those from an ovariectomized female, were characteristic of values obtained form men. It is suggested that a sex-related hormone(s) influences sperimidine and spermine concentrations in females.
在为期4周的时间里，对3名男性、4名女性和1名卵巢切除女性的全血中高氯酸可提取的亚精胺和精胺浓度进行了测定。个体男性的亚精胺/精胺比值波动很小，所研究的3名男性中的每一位都得到了相似的值。男性亚精胺和精胺浓度虽然对每个男性来说是稳定的，但在不同个体之间有所不同。与男性相比，个体女性的亚精胺/精胺比值以及个体浓度波动很大；女性的比值似乎随着月经周期而升降。从服用口服避孕药的正常女性以及卵巢切除女性获得的亚精胺/精胺比值具有男性所得值的特征。有人提出，一种与性别相关的激素会影响女性体内亚精胺和精胺的浓度。
