Gillum R F, Mussolino M E, Madans J H
Office of Analysis, Epidemiology and Health Promotion, Centers for Disease Control and Prevention, Hyattsville, Maryland 20782, USA.
J Natl Med Assoc. 2001 Apr;93(4):124-8.
We sought to test the hypothesis that increased consumption of fish is associated with decreased incidence of essential hypertension. Data on fish consumption and incidence of hypertension from a national cohort of 5,394 blacks and whites normotensive at baseline and followed 10 years in the NHANES I Epidemiologic Follow-up Study (NHEFS) were analyzed. Our results showed that whites aged 25-74 years had no significant association of fish consumption with incidence of hypertension. In black women, after adjusting for multiple risk factors, those who increased their fish intake from <1 time/week to > or = 1 time/week had RR = 0.42, 95% CI 0.22-0.81, p = 0.009. However, those with high intake both times had adjusted RR = 0.75, 95% CI 0.45-1.26, p = 0.28. No consistent significant associations of fish consumption with hypertension incidence were found, perhaps because fish consumption in this population was low. Further studies are needed in blacks.
我们试图验证鱼类摄入量增加与原发性高血压发病率降低相关这一假设。分析了美国国家健康与营养检查调查一期流行病学随访研究（NHEFS）中一个由5394名基线血压正常的黑人和白人组成的全国队列的鱼类消费数据和高血压发病率数据，随访时间为10年。我们的结果显示，25 - 74岁的白人中，鱼类消费与高血压发病率之间无显著关联。在黑人女性中，在对多种风险因素进行调整后，那些将鱼类摄入量从每周少于1次增加到每周1次及以上的女性，相对危险度（RR）= 0.42，95%置信区间（CI）为0.22 - 0.81，p = 0.009。然而，那些两次摄入量都高的女性调整后的RR = 0.75，95% CI为0.45 - 1.26，p = 0.28。未发现鱼类消费与高血压发病率之间存在一致的显著关联，这可能是因为该人群的鱼类消费量较低。黑人中还需要进一步研究。
