Christiansen J, Holst J J, Rokkjaer M
Scand J Gastroenterol. 1976;11(2):219-24.
The administration of hypertonic glucose and saline and of fat intrajejunally in man caused a marked and almost identical inhibition of pentagastrin-stimulated gastric acid secretion. Hypertonic glucose administered intrajejunally in Heidenhain pouch dogs resulted in an equal inhibition of pentagastrin-induced acid secretion from the pouch and the main stomach, whereas hypertonic saline had no effect. The study demonstrates the existence of potent jejunal inhibitors of gastric secretion, which seem to operate independently of vagal innervation.
在人体空肠内给予高渗葡萄糖、生理盐水和脂肪，可显著且几乎同等程度地抑制五肽胃泌素刺激的胃酸分泌。在海登海因小胃犬的空肠内给予高渗葡萄糖，可同等程度地抑制小胃和主胃中五肽胃泌素诱导的胃酸分泌，而高渗盐水则无此作用。该研究表明存在强大的空肠胃酸分泌抑制剂，其作用似乎独立于迷走神经支配。
