Hannay W T, Sharp F, McAllister T A, Perman M G
Scott Med J. 1976 Sep;20(5):265-8. doi: 10.1177/003693307502000519.
A clinical evaluation of a new cephalosporin, cephazolin, in obstetric patients is presented. Sixteen cardiac patients received the drug prophylactically as antibiotic cover during labour. Eighteen patients with miscellaneous antenatal and puerperal infections received the drug as primary treatment. The data obtained indicate adequate serum and tissue levels with the dose used, and corresponding clinical response. The impression is of a safe and efficaceous drug in the described obstetric situations requiring antibiotic therapy. It may be given prophylactically and with confidence to the cardiac patient in labour.
本文介绍了一种新型头孢菌素——头孢唑林在产科患者中的临床评估。16名心脏病患者在分娩期间接受该药物作为抗生素预防性覆盖。18名患有各种产前和产后感染的患者接受该药物作为主要治疗。获得的数据表明，所用剂量可使血清和组织水平充足，并伴有相应的临床反应。在所描述的需要抗生素治疗的产科情况下，该药给人的印象是一种安全有效的药物。对于正在分娩的心脏病患者，可以放心地预防性使用该药。
