• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Transcription of genes encoding trans-acting factors required for rRNA maturation/ribosomal subunit assembly is coordinately regulated with ribosomal protein genes and involves Rap1 in Saccharomyces cerevisiae.在酿酒酵母中，编码rRNA成熟/核糖体亚基组装所需反式作用因子的基因转录与核糖体蛋白基因协同调控，且涉及Rap1。
Nucleic Acids Res. 2003 Apr 1;31(7):1969-73. doi: 10.1093/nar/gkg278.
2
Repression of rRNA synthesis due to a secretory defect requires the C-terminal silencing domain of Rap1p in Saccharomyces cerevisiae.由于分泌缺陷导致的rRNA合成抑制需要酿酒酵母中Rap1p的C末端沉默结构域。
Nucleic Acids Res. 2001 Aug 15;29(16):3297-303. doi: 10.1093/nar/29.16.3297.
3
Transcriptional elements involved in the repression of ribosomal protein synthesis.参与核糖体蛋白合成抑制的转录元件。
Mol Cell Biol. 1999 Aug;19(8):5393-404. doi: 10.1128/MCB.19.8.5393.
4
Assembly of regulatory factors on rRNA and ribosomal protein genes in Saccharomyces cerevisiae.酿酒酵母中调控因子在核糖体RNA和核糖体蛋白基因上的组装
Mol Cell Biol. 2007 Oct;27(19):6686-705. doi: 10.1128/MCB.00876-07. Epub 2007 Jul 23.
5
Gcn4p-mediated transcriptional repression of ribosomal protein genes under amino-acid starvation.氨基酸饥饿下 Gcn4p 介导的核糖体蛋白基因转录抑制。
EMBO J. 2011 Mar 2;30(5):859-72. doi: 10.1038/emboj.2010.332. Epub 2010 Dec 24.
6
Identification of a transcriptional activation domain in yeast repressor activator protein 1 (Rap1) using an altered DNA-binding specificity variant.利用具有改变的DNA结合特异性的变体鉴定酵母阻遏激活蛋白1（Rap1）中的转录激活结构域。
J Biol Chem. 2017 Apr 7;292(14):5705-5723. doi: 10.1074/jbc.M117.779181. Epub 2017 Feb 14.
7
Growth-regulated recruitment of the essential yeast ribosomal protein gene activator Ifh1.生长调节的必需酵母核糖体蛋白基因激活因子Ifh1的募集
Nature. 2004 Dec 23;432(7020):1058-61. doi: 10.1038/nature03200.
8
SSB, encoding a ribosome-associated chaperone, is coordinately regulated with ribosomal protein genes.编码一种核糖体相关伴侣蛋白的SSB与核糖体蛋白基因协同调控。
J Bacteriol. 1999 May;181(10):3136-43. doi: 10.1128/JB.181.10.3136-3143.1999.
9
Yeast ribosomal protein L40 assembles late into precursor 60 S ribosomes and is required for their cytoplasmic maturation.酵母核糖体蛋白 L40 晚期组装到前体 60S 核糖体中，并需要其细胞质成熟。
J Biol Chem. 2012 Nov 2;287(45):38390-407. doi: 10.1074/jbc.M112.400564. Epub 2012 Sep 20.
10
Fine-structure analysis of ribosomal protein gene transcription.核糖体蛋白基因转录的精细结构分析
Mol Cell Biol. 2006 Jul;26(13):4853-62. doi: 10.1128/MCB.02367-05.

引用本文的文献

1
Sphingolipid/Pkh1/2-TORC1/Sch9 Signaling Regulates Ribosome Biogenesis in Tunicamycin-Induced Stress Response in Yeast.鞘脂类/Pkh1/2-TORC1/Sch9 信号通路调节酵母衣霉素诱导的应激反应中的核糖体生物发生。
Genetics. 2019 May;212(1):175-186. doi: 10.1534/genetics.118.301874. Epub 2019 Mar 1.
2
Feedback regulation of ribosome assembly.核糖体组装的反馈调节
Curr Genet. 2018 Apr;64(2):393-404. doi: 10.1007/s00294-017-0764-x. Epub 2017 Oct 11.
3
The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation.核糖体组装基因网络受转录延伸的反馈调节控制。
Nucleic Acids Res. 2017 Sep 19;45(16):9302-9318. doi: 10.1093/nar/gkx529.
4
Hierarchical recruitment into nascent ribosomes of assembly factors required for 27SB pre-rRNA processing in Saccharomyces cerevisiae.酵母 27SB pre-rRNA 加工所需的组装因子的新生核糖体的层次募集。
Nucleic Acids Res. 2012 Sep 1;40(17):8646-61. doi: 10.1093/nar/gks609. Epub 2012 Jun 26.
5
Genome-wide integration on transcription factors, histone acetylation and gene expression reveals genes co-regulated by histone modification patterns.全基因组转录因子、组蛋白乙酰化和基因表达整合揭示了受组蛋白修饰模式共同调控的基因。
PLoS One. 2011;6(7):e22281. doi: 10.1371/journal.pone.0022281. Epub 2011 Jul 29.
6
Evolutionarily conserved function of RRP36 in early cleavages of the pre-rRNA and production of the 40S ribosomal subunit.RRP36 在 pre-rRNA 的早期切割和 40S 核糖体亚基的产生中具有进化保守的功能。
Mol Cell Biol. 2010 Mar;30(5):1130-44. doi: 10.1128/MCB.00999-09. Epub 2009 Dec 28.
7
Dynamics of the yeast transcriptome during wine fermentation reveals a novel fermentation stress response.葡萄酒发酵过程中酵母转录组的动态变化揭示了一种新的发酵应激反应。
FEMS Yeast Res. 2008 Feb;8(1):35-52. doi: 10.1111/j.1567-1364.2007.00338.x.
8
Yeast Rrp14p is a nucleolar protein involved in both ribosome biogenesis and cell polarity.酵母Rrp14p是一种参与核糖体生物合成和细胞极性的核仁蛋白。
RNA. 2007 Nov;13(11):1977-87. doi: 10.1261/rna.553807. Epub 2007 Sep 5.
9
Design principles of molecular networks revealed by global comparisons and composite motifs.通过全局比较和复合基序揭示的分子网络设计原则
Genome Biol. 2006;7(7):R55. doi: 10.1186/gb-2006-7-7-r55.
10
Genome-wide transcription profiling of the early phase of biofilm formation by Candida albicans.白色念珠菌生物膜形成早期的全基因组转录谱分析。
Eukaryot Cell. 2005 Sep;4(9):1562-73. doi: 10.1128/EC.4.9.1562-1573.2005.

本文引用的文献

1
Transcriptional regulatory networks in Saccharomyces cerevisiae.酿酒酵母中的转录调控网络。
Science. 2002 Oct 25;298(5594):799-804. doi: 10.1126/science.1075090.
2
90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors.90S前核糖体包含35S前体rRNA、U3核仁小核糖核蛋白颗粒和40S亚基加工因子，但主要缺乏60S合成因子。
Mol Cell. 2002 Jul;10(1):105-15. doi: 10.1016/s1097-2765(02)00579-8.
3
Systematic identification of pathways that couple cell growth and division in yeast.酵母中连接细胞生长与分裂的通路的系统鉴定。
Science. 2002 Jul 19;297(5580):395-400. doi: 10.1126/science.1070850. Epub 2002 Jun 27.
4
A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.一种参与18S核糖体RNA生物合成所需的大型核仁U3核糖核蛋白。
Nature. 2002 Jun 27;417(6892):967-70. doi: 10.1038/nature00769. Epub 2002 Jun 9.
5
Making ribosomes.制造核糖体。
Curr Opin Cell Biol. 2002 Jun;14(3):313-8. doi: 10.1016/s0955-0674(02)00336-8.
6
Rpf2p, an evolutionarily conserved protein, interacts with ribosomal protein L11 and is essential for the processing of 27 SB Pre-rRNA to 25 S rRNA and the 60 S ribosomal subunit assembly in Saccharomyces cerevisiae.Rpf2p是一种进化上保守的蛋白质，它与核糖体蛋白L11相互作用，对于酿酒酵母中27S前体rRNA加工成25S rRNA以及60S核糖体亚基组装至关重要。
J Biol Chem. 2002 Aug 9;277(32):28780-6. doi: 10.1074/jbc.M203399200. Epub 2002 Jun 4.
7
Normal assembly of 60 S ribosomal subunits is required for the signaling in response to a secretory defect in Saccharomyces cerevisiae.酿酒酵母中60 S核糖体亚基的正常组装是响应分泌缺陷进行信号传导所必需的。
J Biol Chem. 2002 May 24;277(21):18334-9. doi: 10.1074/jbc.M201667200. Epub 2002 Mar 13.
8
Ssf1p prevents premature processing of an early pre-60S ribosomal particle.Ssf1p可防止早期60S核糖体前体颗粒的过早加工。
Mol Cell. 2002 Feb;9(2):341-51. doi: 10.1016/s1097-2765(02)00458-6.
9
EBP2 is a member of the yeast RRB regulon, a transcriptionally coregulated set of genes that are required for ribosome and rRNA biosynthesis.EBP2是酵母RRB调控子的成员，RRB调控子是一组转录共调控基因，对于核糖体和rRNA生物合成是必需的。
Mol Cell Biol. 2001 Dec;21(24):8638-50. doi: 10.1128/MCB.21.24.8638-8650.2001.
10
Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps.Nog2p，一种假定的与前60S亚基相关且参与60S后期成熟步骤所必需的GTP酶。
EMBO J. 2001 Nov 15;20(22):6475-84. doi: 10.1093/emboj/20.22.6475.

在酿酒酵母中，编码rRNA成熟/核糖体亚基组装所需反式作用因子的基因转录与核糖体蛋白基因协同调控，且涉及Rap1。

Transcription of genes encoding trans-acting factors required for rRNA maturation/ribosomal subunit assembly is coordinately regulated with ribosomal protein genes and involves Rap1 in Saccharomyces cerevisiae.

作者信息

Miyoshi Keita, Shirai Chiharu, Mizuta Keiko

机构信息

Department of Bioresource Science and Technology, Graduate School of Biosphere Science, Hiroshima University, Kagamiyama 1-4-4, Higashi-Hiroshima 739-8528, Japan.

出版信息

Nucleic Acids Res. 2003 Apr 1;31(7):1969-73. doi: 10.1093/nar/gkg278.

DOI:10.1093/nar/gkg278
PMID:12655014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC152794/
Abstract

We demonstrate that the genes encoding trans- acting factors essential for pre-rRNA processing/ribosomal subunit assembly are responsive to various kinds of stresses such as heat shock, nitrogen deprivation and a secretory defect, in coordination with ribosomal protein genes in Saccharomyces cerevisiae. The rap1-17 mutation, which produces the C-terminally truncated protein of a transcriptional factor Rap1p, affects transcriptional repression of the trans-acting factor genes due to a secretory defect as shown previously for both ribosomal protein and rRNA genes.

摘要

我们证明，在酿酒酵母中，编码前体rRNA加工/核糖体亚基组装所必需的反式作用因子的基因，与核糖体蛋白基因协同，对热休克、氮剥夺和分泌缺陷等各种应激作出反应。rap1-17突变产生转录因子Rap1p的C末端截短蛋白，如先前对核糖体蛋白和rRNA基因所示，由于分泌缺陷，该突变影响反式作用因子基因的转录抑制。