大鼠急性精原细胞X线照射后的显性致死效应
Dominant lethals following acute spermatogonial X-irradiation in the rat.
作者信息
Baev I, Bajrakova A
出版信息
Strahlentherapie. 1976 Apr;151(4):382-5.
PMID:1265787
Abstract
Spermatogonial X-irradiation with 0, 400 or 600 R in adult rats and 200 R in fetal rats was carried out to assess genetic damage by the test of induced dominant lethality. From postimplantation embryonic losses observed, dominant lethal rates were established to be significantly raised by a dose of 400 or 600 R. With 200 R given either to adult or to fetal rats, no excess was detected in embryonic death rates.
摘要
对成年大鼠进行0、400或600伦琴的精原细胞X射线照射，对胎鼠进行200伦琴的照射，通过诱导显性致死试验评估遗传损伤。根据观察到的植入后胚胎损失情况，确定400或600伦琴的剂量可显著提高显性致死率。对成年大鼠或胎鼠给予200伦琴的照射，未检测到胚胎死亡率有增加。
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