新型头孢菌素抗生素头孢呋辛与头孢噻啶、头孢噻吩和头孢孟多的抗菌活性比较。
Antibacterial activity of cefuroxime, a new cephalosporin antibiotic, compared with that of cephaloridine, cephalothin, and cefamandole.
作者信息
Eykyn S, Jenkins C, King A, Phillips I
出版信息
Antimicrob Agents Chemother. 1976 Apr;9(4):690-5. doi: 10.1128/AAC.9.4.690.
Abstract
The in vitro activity of cefuroxime, a new cephalosporin derivative, was compared with that of cephaloridine, cephalothin, and cefamandole against strains of gram-positive and gram-negative bacteria recently isolated from clinical sources. Cefuroxime showed very similar activity to cefamandole against Staphylococcus aureus, Haemophilus influenzae, and most members of the Enterobacteriaceae. It was more active than cefamandole against gonococci, pneumococci, and most streptococci. Increasing the inoculum size appeared to have less effect on the minimum inhibitory concentrations of cefuroxime for gram-negative bacilli than has been found with the other cephalosporin derivatives, and minimum bactericidal concentrations of cefuroxime were only marginally greater than minimum inhibitory concentrations.
摘要
将一种新型头孢菌素衍生物头孢呋辛的体外活性与头孢噻啶、头孢噻吩和头孢孟多针对近期从临床分离出的革兰氏阳性菌和革兰氏阴性菌菌株的活性进行了比较。头孢呋辛对金黄色葡萄球菌、流感嗜血杆菌和大多数肠杆菌科成员显示出与头孢孟多非常相似的活性。它对淋球菌、肺炎球菌和大多数链球菌的活性比头孢孟多更强。与其他头孢菌素衍生物相比，增加接种量对头孢呋辛对革兰氏阴性杆菌的最低抑菌浓度影响似乎较小，且头孢呋辛的最低杀菌浓度仅略高于最低抑菌浓度。
相似文献
1
Antibacterial activity of cefuroxime, a new cephalosporin antibiotic, compared with that of cephaloridine, cephalothin, and cefamandole.新型头孢菌素抗生素头孢呋辛与头孢噻啶、头孢噻吩和头孢孟多的抗菌活性比较。
Antimicrob Agents Chemother. 1976 Apr;9(4):690-5. doi: 10.1128/AAC.9.4.690.
2
Antibacterial activity of cefamandole, a new cephalosporin antibiotic, compared with that of cephaloridine, cephalothin, and cephalexin.新型头孢菌素抗生素头孢孟多与头孢噻啶、头孢噻吩和头孢氨苄的抗菌活性比较。
Antimicrob Agents Chemother. 1973 Jun;3(6):657-61. doi: 10.1128/AAC.3.6.657.
3
The activity of cephalosporins on beta-lactamase-producing Neisseria gonorrhoeae.头孢菌素对产β-内酰胺酶淋病奈瑟菌的活性。
Scand J Infect Dis Suppl. 1978(13):23-6.
4
In vitro comparison of cefoxitin, cefamandole, cephalexin, and cephalothin.头孢西丁、头孢孟多、头孢氨苄和头孢噻吩的体外比较
Antimicrob Agents Chemother. 1976 Jun;9(6):994-9. doi: 10.1128/AAC.9.6.994.
5
Comparison of the in vitro activity of several cephalosporin antibiotics against gram-negative and gram-positive bacteria resistant to cephaloridine.几种头孢菌素抗生素对耐头孢噻啶的革兰氏阴性菌和革兰氏阳性菌的体外活性比较。
Antimicrob Agents Chemother. 1976 Sep;10(3):507-10. doi: 10.1128/AAC.10.3.507.
6
Comparison of the antibacterial activity of nine cephalosporins against Enterobacteriaceae and nonfermentative gram-negative bacilli.九种头孢菌素对肠杆菌科细菌和非发酵革兰氏阴性杆菌的抗菌活性比较。
Antimicrob Agents Chemother. 1976 Oct;10(4):657-63. doi: 10.1128/AAC.10.4.657.
7
Evaluation of antibacterial activities of cephalosporin antibiotics: cefazolin, cephaloridine, cephalothin, and cephalexin.头孢菌素类抗生素的抗菌活性评估：头孢唑林、头孢噻啶、头孢噻吩和头孢氨苄。
Zhonghua Min Guo Wei Sheng Wu Xue Za Zhi. 1975 Mar;8(1):1-11.
8
Cefuroxime, a new parenteral cephalosporin: collaborative in vitro susceptibility comparison with cephalothin against 5,887 clinical bacterial isolates.头孢呋辛，一种新型胃肠外使用的头孢菌素：与头孢噻吩针对5887株临床分离细菌进行的体外药敏协同比较
Antimicrob Agents Chemother. 1977 Jul;12(1):47-50. doi: 10.1128/AAC.12.1.47.
9
Comparative study of the in vitro antibacterial activity of cefoxitin, cefuroxine, and cephaloridine.头孢西丁、头孢呋辛和头孢噻啶体外抗菌活性的比较研究。
Antimicrob Agents Chemother. 1976 Mar;9(3):506-10. doi: 10.1128/AAC.9.3.506.
10
Activity of cefamandole and other cephalosporins against aerobic and anaerobic bacteria.头孢孟多及其他头孢菌素对需氧菌和厌氧菌的活性。
Antimicrob Agents Chemother. 1976 May;9(5):852-5. doi: 10.1128/AAC.9.5.852.
引用本文的文献
1
The Chemical Relationship Among Beta-Lactam Antibiotics and Potential Impacts on Reactivity and Decomposition.β-内酰胺类抗生素之间的化学关系及其对反应活性和分解的潜在影响。
Front Microbiol. 2022 Mar 24;13:807955. doi: 10.3389/fmicb.2022.807955. eCollection 2022.
2
Cefuroxime in the treatment of bacterial infections in seriously ill patients admitted to an intensive care unit.头孢呋辛用于治疗入住重症监护病房的重症患者的细菌感染。
Proc R Soc Med. 1977;70(Suppl 9):86-9. doi: 10.1177/00359157770700S917.
3
The in vitro and in vivo Antibacterial Activity of Cefuroxime.头孢呋辛的体外和体内抗菌活性
Proc R Soc Med. 1977;70(Suppl 9):56-62. doi: 10.1177/00359157770700S911.
4
Cefuroxime: pharmacokinetic study in bronchial secretions.头孢呋辛：支气管分泌物中的药代动力学研究
Proc R Soc Med. 1977;70(Suppl 9):34-7. doi: 10.1177/00359157770700S907.
5
Experimental investigations of cefuroxime in renal tolerance and therapeutic efficacy in pyelonephritis.头孢呋辛对肾盂肾炎肾耐受性及治疗效果的实验研究。
Proc R Soc Med. 1977;70(Suppl 9):134-8. doi: 10.1177/00359157770700S931.
6
Clinical profile of cefuroxime in sixty-four patients.64例患者使用头孢呋辛的临床资料
Proc R Soc Med. 1977;70(Suppl 9):111-7. doi: 10.1177/00359157770700S925.
7
An evaluation of cefuroxime in internal medicine.头孢呋辛在内科的应用评估。
Proc R Soc Med. 1977;70(Suppl 9):107-10. doi: 10.1177/00359157770700S924.
8
Cefuroxime: a clinical evaluation.头孢呋辛：临床评估。
Proc R Soc Med. 1977;70(Suppl 9):103-6. doi: 10.1177/00359157770700S923.
9
Comparative intraocular penetration of topical and injected cefuroxime.局部应用与注射用头孢呋辛的眼内穿透性比较。
Br J Ophthalmol. 1996 Aug;80(8):685-8. doi: 10.1136/bjo.80.8.685.
10
Pharmacokinetics of cefuroxime in normal and impaired renal function: comparison of high-pressure liquid chromatography and microbiological assays.头孢呋辛在肾功能正常和受损患者中的药代动力学：高压液相色谱法与微生物测定法的比较
Antimicrob Agents Chemother. 1981 Mar;19(3):443-9. doi: 10.1128/AAC.19.3.443.
本文引用的文献
1
Antibacterial activity of cefamandole, a new cephalosporin antibiotic, compared with that of cephaloridine, cephalothin, and cephalexin.新型头孢菌素抗生素头孢孟多与头孢噻啶、头孢噻吩和头孢氨苄的抗菌活性比较。
Antimicrob Agents Chemother. 1973 Jun;3(6):657-61. doi: 10.1128/AAC.3.6.657.
2
Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate.一种使用显色头孢菌素底物检测β-内酰胺酶的新方法。
Antimicrob Agents Chemother. 1972 Apr;1(4):283-8. doi: 10.1128/AAC.1.4.283.
3
Relationship between beta-lactamase production by Haemophilus influenzae and sensitivities to penicillins and cephalosporins.流感嗜血杆菌产生β-内酰胺酶与对青霉素和头孢菌素敏感性之间的关系。
J Antimicrob Chemother. 1975 Mar;1(1):79-84. doi: 10.1093/jac/1.1.79.
4
Susceptibility of Anaerobic bacteria to carbenicillin, cefoxitin, and related drugs.厌氧菌对羧苄青霉素、头孢西丁及相关药物的敏感性。
J Infect Dis. 1975 Apr;131(4):417-22. doi: 10.1093/infdis/131.4.417.
Zotero 插件