Bouljihad Mostafa, Lindeman Cindy J, Hayden David W
Department of Veterinary Diagnostic Medicine, Minnesota Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Minnesota, 1333 Gortner Avenue, St. Paul, MN 55108, USA.
J Vet Diagn Invest. 2002 Jan;14(1):70-2. doi: 10.1177/104063870201400116.
A 6-month-old, castrated male domestic cat with progressive neurological signs of 2-3 weeks duration was necropsied. Macroscopic findings were restricted to the brain and included irregularly shaped, well-delineated but unencapsulated areas of intense black pigmentation involving the rostral portion of both cerebral hemispheres. Microscopically, numerous brown, oblong, segmented branching hyphae and conidial-like structures and extensive pyogranulomatous inflammation were identified throughout the cerebral lesion and in adjacent blood vessels. Hyphae and oval conidia were best demonstrated with either Gomori methenamine silver or periodic acid-Schiff stain. Fungal infection in the brain of this cat was unrelated to any concurrent immunodeficiency syndrome or immunosuppressive treatment. This report deals with a case of cerebral phaeohyphomycosis from which a different species of dematiaceous fungus, Cladophialophora bantiana, was isolated and identified.
对一只6个月大、已去势的雄性家猫进行了尸检，该猫出现进行性神经症状达2至3周。宏观检查结果仅限于脑部，包括形状不规则、边界清晰但无包膜的强烈黑色色素沉着区域，累及双侧大脑半球的前部。显微镜下，在整个脑部病变及相邻血管中发现了大量棕色、椭圆形、分节的分支菌丝和分生孢子样结构，以及广泛的脓性肉芽肿性炎症。菌丝和椭圆形分生孢子用Gomori六胺银染色或过碘酸-希夫染色显示效果最佳。这只猫脑部的真菌感染与任何并发的免疫缺陷综合征或免疫抑制治疗无关。本报告涉及一例脑部暗色丝孢霉病病例，从中分离并鉴定出一种不同的暗色真菌——班替枝孢瓶霉。
