Tintelnot K, de Hoog G S, Haase G
Konsiliarlabor für Kryptokokkose, Scedosporiose und importierte Systemmykosen, Robert Koch-Institut, Nordufer 20, 13353, Berlin, Deutschland,
Pathologe. 2013 Nov;34(6):534-9. doi: 10.1007/s00292-013-1830-x.
The majority of mycoses which lead to mycotic tumors in patients without any predisposing underlying disease are either caused by Cryptococcus gattii and C. neoformans or by dematiaceous fungi which include Cladophialophora bantiana, Ramichloridium mackenziei, Exophiala and Fonsecaea species. The detection of hyphae in granuloma in the brain should lead to screening for pigmented fungi, which are recognized best in hematoxylin eosin (HE) or sometimes also in periodic acid-Schiff (PAS) stained sections. In patients who survive a near drowning accident and those who develop brain abscesses, scedosporiosis should always be considered as a possible infection.
在没有任何易感基础疾病的患者中，导致真菌性肿瘤的大多数真菌病要么由加氏隐球菌和新型隐球菌引起，要么由暗色真菌引起，其中包括班替枝孢瓶霉、麦肯齐支顶孢、外瓶霉属和瓶霉属物种。在大脑肉芽肿中检测到菌丝应促使对色素真菌进行筛查，色素真菌在苏木精伊红（HE）染色切片中最易识别，有时在过碘酸希夫（PAS）染色切片中也能较好识别。在近乎溺水事故后存活的患者以及发生脑脓肿的患者中，应始终将波氏假阿利什霉病视为可能的感染。
