Sulkowski Mark S, Thomas David L
Viral Hepatitis Section, Division of Infectious Diseases, Johns Hopkins School of Medicine, Suite 102, 424 North Bond Street, Baltimore, MD 21231, USA.
Clin Liver Dis. 2003 Feb;7(1):179-94. doi: 10.1016/s1089-3261(02)00074-0.
Hepatitis C virus infection is common in people with HIV and represents an increasingly important public health problem. Thus, although there remains a considerable amount of uncertainty about whom to treat and the best way to treat, providers must use available information generated chiefly from patients without HIV to manage HCV infection in coinfected patients. Future efforts should include prospective studies that demonstrate the natural history and optimal management of HIV/HCV-coinfected patients, including the feasibility of liver transplantation.
丙型肝炎病毒感染在艾滋病毒感染者中很常见,是一个日益重要的公共卫生问题。因此,尽管在治疗对象和最佳治疗方法方面仍存在相当多的不确定性,但医疗服务提供者必须利用主要来自未感染艾滋病毒患者的现有信息来管理合并感染患者的丙型肝炎病毒感染。未来的工作应包括前瞻性研究,以证明艾滋病毒/丙型肝炎病毒合并感染患者的自然病程和最佳管理方法,包括肝移植的可行性。