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两种检测乙型肝炎抗原(HBAg)方法的比较研究:双重连续对流免疫电泳(DCIEP)和Ausria II - 125I放射免疫测定法。

Comparative study of two methods for hepatitis B antigen (HBAg) detection: double sequential counterimmunoelectrophoresis (DCIEP) and Ausria II-125I radioimmunoassay.

作者信息

Szántay J, Dejica D, Abrudan O

出版信息

Clin Chim Acta. 1976 May 17;69(1):117-9. doi: 10.1016/0009-8981(76)90480-0.

Abstract

Double sequential counterimmunoelectrophoresis (DCIEP) (an improved method that we have developed) and Ausria II-125I (an indirect solid-phase radioimmunoassay) were compared for HBAg detection in chronic liver diseases. 26.8% of the patients were positive using DCIEP and 41.8% were positive with Ausria II125I. The conventional counterimmunoelectrophoresis (CIEP) is less sensitive than DCIEP, the level of positive results being 18.8% (P less than 0.001)9

摘要

采用双顺序对流免疫电泳法(DCIEP,我们研发的一种改良方法)和Ausria II - 125I(一种间接固相放射免疫测定法)对慢性肝病患者的乙肝表面抗原(HBAg)进行检测,并作比较。采用DCIEP检测时,26.8%的患者呈阳性;采用Ausria II - 125I检测时,41.8%的患者呈阳性。传统的对流免疫电泳法(CIEP)不如DCIEP灵敏,阳性结果比例为18.8%(P<0.001)。

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