Bayley Peter J, Hopkins Ramona O, Squire Larry R
University of California, San Diego, La Jolla, California 92093, USA.
Neuron. 2003 Apr 10;38(1):135-44. doi: 10.1016/s0896-6273(03)00156-9.
Current views about the organization of human memory make strikingly different predictions about the integrity of remote autobiographical memory following damage to the medial temporal lobe. We have carried out a detailed analysis of narrative content in memory-impaired patients for whom neuropsychological and neuroanatomical information is available. All eight patients were able to recall detailed memories from their early lives. The recollections of the patients and the recollections of 25 matched controls contained the same number of details (+/-5%) and were also similar by several other measures. The results support the view that autobiographical memories eventually become independent of the medial temporal lobe as time passes after learning. A number of other considerations suggest that the neocortex ultimately supports the capacity for recollecting remote autobiographical memory.
当前关于人类记忆组织的观点，对于内侧颞叶受损后远程自传体记忆的完整性做出了截然不同的预测。我们对有神经心理学和神经解剖学信息的记忆受损患者的叙述内容进行了详细分析。所有八名患者都能够回忆起他们早年生活中的详细记忆。患者的回忆与25名匹配对照组的回忆包含相同数量的细节（±5%），并且在其他几项指标上也相似。这些结果支持了这样一种观点，即随着学习后时间的推移，自传体记忆最终会独立于内侧颞叶。其他一些考虑因素表明，新皮层最终支持回忆远程自传体记忆的能力。
