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Changing genes; losing lactase.
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Sequence of the precursor of intestinal lactase-phlorizin hydrolase from fetal rat.
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4
Total intestinal lactase and sucrase activities are reduced in aged rats.
J Nutr. 1997 Jul;127(7):1382-7. doi: 10.1093/jn/127.7.1382.
5
Region-specific expression of multiple lactase-phlorizin hydrolase genes in intestine of rabbit.
FEBS Lett. 1993 Dec 20;336(1):70-4. doi: 10.1016/0014-5793(93)81611-3.
6
Immunocytochemical heterogeneity of lactase-phlorizin hydrolase in adult lactase deficiency.
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The human lactase-phlorizin hydrolase gene is located on chromosome 2.
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Lactose intolerance and the genetic regulation of intestinal lactase-phlorizin hydrolase.
FASEB J. 1991 Oct;5(13):2824-32. doi: 10.1096/fasebj.5.13.1916106.
10
Regulation of sucrase and lactase in developing rats: role of nuclear factors that bind to two gene regulatory elements.
Gastroenterology. 1997 Mar;112(3):803-12. doi: 10.1053/gast.1997.v112.pm9041242.

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2
Recovery of enzyme activity in biotinidase deficient individuals during early childhood.
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6
Lactose malabsorption.
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Mendelian randomization in nutritional epidemiology.
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8
The enterocyte microvillus is a vesicle-generating organelle.
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Genetic signatures of strong recent positive selection at the lactase gene.
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2
Regulation of intestine-specific spatiotemporal expression by the rat lactase promoter.
J Biol Chem. 2002 Apr 12;277(15):13099-105. doi: 10.1074/jbc.M112152200. Epub 2002 Jan 25.
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Identification of a variant associated with adult-type hypolactasia.
Nat Genet. 2002 Feb;30(2):233-7. doi: 10.1038/ng826. Epub 2002 Jan 14.
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The prosequence of human lactase-phlorizin hydrolase modulates the folding of the mature enzyme.
J Biol Chem. 2002 Mar 8;277(10):8217-25. doi: 10.1074/jbc.M111500200. Epub 2001 Dec 18.
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Differential activation of intestinal gene promoters: functional interactions between GATA-5 and HNF-1 alpha.
Am J Physiol Gastrointest Liver Physiol. 2001 Jul;281(1):G69-84. doi: 10.1152/ajpgi.2001.281.1.G69.
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Lactase haplotype diversity in the Old World.
Am J Hum Genet. 2001 Jan;68(1):160-172. doi: 10.1086/316924. Epub 2000 Nov 28.
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The homeodomain protein Cdx2 regulates lactase gene promoter activity during enterocyte differentiation.
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