Ouyang Jie, Wang Xiaodong, Zhao Bing, Yuan Xiaofan, Wang Yuchun
State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, P.O. Box 353, Beijing, 100080, China.
J Biotechnol. 2003 Apr 24;102(2):129-34. doi: 10.1016/s0168-1656(03)00019-1.
The rare earth elements Nd, La, Ce at proper concentrations had positive effects on the cell growth of Cistanche deserticola and production of phenylethanoid glycosides (PeG). A mixture of rare earth elements (MRE, La(2)O(3):CeO(2):Pr(6)O(11):Sm(2)O(3)=255:175:3:1, mol/mol) showed the most remarkable effects. After 30 day's culture, 0.02 mmoll(-1) MRE gave the highest content (20.8%) and production (1.6 gl(-1)) of PeG, which were 104 and 167% higher than those obtained in control (without rare earth elements).
适当浓度的稀土元素钕(Nd)、镧(La)、铈(Ce)对肉苁蓉细胞生长和苯乙醇苷(PeG)的产生具有积极影响。稀土元素混合物(MRE,La₂O₃:CeO₂:Pr₆O₁₁:Sm₂O₃ = 255:175:3:1,摩尔/摩尔)显示出最显著的效果。培养30天后,0.02 mmol/L的MRE使PeG的含量最高(20.8%)且产量最高(1.6 g/L),分别比对照(无稀土元素)高出104%和167%。