Fevre D I, Green P H, Barratt P J, Nagy G S
Gut. 1976 Jan;17(1):41-7. doi: 10.1136/gut.17.1.41.
Five cases of early gastric carcinoma (EGC) were seen in 12 months. The clinical features did not provide guide-lines to diagnosis, which depends on air contrast barium studies, endoscopic recognition of early malignancy, adequate biopsies, and their interpretation. Malignancy was present in an average of 60% of the biopsies taken. The most common type of lesion was IIc. The superficial nature of the malignancy was predicted at endoscopy in four cases but was unsuspected in one case which was considered to be advanced carcinoma until the resected specimen was throughly examined microscopically. The excellent prognosis of EGC was discussed. Only conservative surgery need be performed if the superficial nature of the lesion is recognized before operation.
在12个月内共发现5例早期胃癌(EGC)。其临床特征对诊断并无指导作用,诊断主要依靠气钡双重造影、早期恶性病变的内镜识别、足够的活检以及对活检结果的解读。所取活检标本中平均60%存在恶性病变。最常见的病变类型为IIc型。4例在内镜检查时可预测到恶性病变的表浅性质,但有1例未被怀疑,该例在切除标本经显微镜全面检查之前一直被认为是进展期癌。文中还讨论了早期胃癌的良好预后。如果在手术前认识到病变的表浅性质,仅需进行保守性手术。