Scher A I, Lipton R B, Stewart W F
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892-9205, USA.
Neurology. 2003 Apr 22;60(8):1366-8. doi: 10.1212/01.wnl.0000055873.71552.51.
Frequent headache is associated with a variety of sleep disorders. The authors compared the prevalence of snoring in a group of chronic daily headache (CDH) subjects (n = 206) with a control group of episodic headache subjects (n = 507). Habitual snoring was more common in the CDH subjects than in the control subjects (24 vs 14%; p < 0.05); the difference remained after adjusting for factors related to sleep-disordered breathing (OR = 2.9; p < 0.005). If this association proves causal, sleep-disordered breathing may provide a target for therapeutic interventions for chronic daily headache.
频繁头痛与多种睡眠障碍有关。作者比较了一组慢性每日头痛（CDH）患者（n = 206）与一组发作性头痛患者（对照组，n = 507）的打鼾发生率。习惯性打鼾在CDH患者中比在对照组中更常见（24% 对 14%；p < 0.05）；在调整与睡眠呼吸障碍相关的因素后，差异仍然存在（OR = 2.9；p < 0.005）。如果这种关联被证明具有因果关系，那么睡眠呼吸障碍可能为慢性每日头痛的治疗干预提供一个靶点。
