来自可食厚皮树的新型二氢烷基己烯酮。

New dihydroalkylhexenones from Lannea edulis.

作者信息

Queiroz Emerson F, Kuhl Celestina, Terreaux Christian, Mavi Stephen, Hostettmann Kurt

机构信息

Institute of Pharmacognosy and Phytochemistry, University of Lausanne, BEP, CH-1015 Lausanne, Switzerland.

出版信息

J Nat Prod. 2003 Apr;66(4):578-80. doi: 10.1021/np0202428.

DOI:10.1021/np0202428

PMID:12713423

Abstract

Activity-guided isolation of radical-scavenging compounds from the dichloromethane extract of the root bark of Lannea edulis led to isolation of two known bioactive alkylphenols [cardonol 7 (1) and cardonol 13 (2)], and three new dihydroalkylhexenones were also isolated (3-5). Their structures were elucidated by spectroscopic and chemical methods. The absolute configuration of 4 was determined by the Mosher ester method.

摘要

对可食榄仁树根皮二氯甲烷提取物进行活性导向分离，得到两种已知的具有生物活性的烷基酚[卡多酚7（1）和卡多酚13（2）]，还分离出三种新的二氢烷基己烯酮（3 - 5）。通过光谱和化学方法阐明了它们的结构。4的绝对构型通过莫舍尔酯法确定。