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[微波辐射对小鼠脂质过氧化及神经递质含量的影响]

[Effects of microwave radiation on lipid peroxidation and the content of neurotransmitters in mice].

作者信息

Cao Z, Zhang H, Tao Y, Liu J

机构信息

Institute of Environmental Health Monitoring, Chinese Academy of Preventive Medicine, Beijing 100021, China.

出版信息

Wei Sheng Yan Jiu. 2000 Jan 30;29(1):28-9.

PMID:12725036
Abstract

Male LACA mice were exposed to 900 MHz microwaves at the power densities of 0,1,2 and 5 mW/cm2. The resulting specific absorption rates(SARs) were 0, 0.22, 0.44 and 1.10 W/kg respectively. Animals were exposed at the dosage of 1 hour a day for 35 days. The results showed that the activity of glutathione peroxidase (GSH-Px) increased and the concentration of malondialdehyde (MDA) decreased in blood, and the concentration of noradrenaline (NE) increased in brains in the microwave exposed groups at 1 mW/cm2 compared with the sham-exposed group. But no significant changes were found in the microwave exposed groups at 2 and 5 mW/cm2. No significant changes of the concentrations of 5-hydroxytryptamine(5-HT), 5-hydroxyindole acetic acid(5-HIAA) and dopamie(DA) in brains were found.

摘要

将雄性LACA小鼠暴露于功率密度为0、1、2和5 mW/cm² 的900 MHz微波中。由此产生的比吸收率(SARs)分别为0、0.22、0.44和1.10 W/kg。动物每天以1小时的剂量暴露35天。结果显示,与假暴露组相比,1 mW/cm² 微波暴露组血液中谷胱甘肽过氧化物酶(GSH-Px)活性增加,丙二醛(MDA)浓度降低,大脑中去甲肾上腺素(NE)浓度增加。但在2和5 mW/cm² 微波暴露组中未发现显著变化。大脑中5-羟色胺(5-HT)、5-羟吲哚乙酸(5-HIAA)和多巴胺(DA)的浓度未发现显著变化。

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