Deshmukh Pravin Suryakantrao, Banerjee Basu Dev, Abegaonkar Mahesh Pandurang, Megha Kanu, Ahmed Rafat Sultana, Tripathi Ashok Kumar, Mediratta Pramod Kumari
Environmental Biochemistry and Molecular Biology Laboratory, Department of Biochemistry, University College of Medical Sciences & G.T.B. Hospital, University of Delhi, Dilshad Garden, Delhi 110095, India.
Indian J Biochem Biophys. 2013 Apr;50(2):114-9.
Use of wireless communicating devices is increasing at an exponential rate in present time and is raising serious concerns about possible adverse effects of microwave (MW) radiation emitted from these devices on human health. The present study aimed to evaluate the effects of 900 MHz MW radiation exposure on cognitive function and oxidative stress in blood of Fischer rats. Animals were divided into two groups (6 animals/group): Group I (MW-exposed) and Group II (Sham-exposed). Animals were subjected to MW exposure (Frequency 900 MHz; specific absorption rate 8.4738 x 10(-5) W/kg) in Gigahertz transverse electromagnetic cell (GTEM) for 30 days (2 h/day, 5 days/week). Subsequently, cognitive function and oxidative stress parameters were examined for each group. Results showed significant impairment in cognitive function and increase in oxidative stress, as evidenced by the increase in levels of MDA (a marker of lipid peroxidation) and protein carbonyl (a marker of protein oxidation) and unaltered GSH content in blood. Thus, the study demonstrated that low level MW radiation had significant effect on cognitive function and was also capable of leading to oxidative stress.
目前，无线通信设备的使用正呈指数级增长，这引发了人们对这些设备发出的微波（MW）辐射可能对人体健康产生的不利影响的严重担忧。本研究旨在评估900 MHz微波辐射暴露对Fischer大鼠血液中认知功能和氧化应激的影响。将动物分为两组（每组6只动物）：第一组（微波暴露组）和第二组（假暴露组）。动物在千兆赫兹横向电磁室（GTEM）中接受微波暴露（频率900 MHz；比吸收率8.4738×10⁻⁵ W/kg），持续30天（每天2小时，每周5天）。随后，对每组动物的认知功能和氧化应激参数进行检测。结果显示，认知功能显著受损，氧化应激增加，血液中丙二醛（脂质过氧化标志物）和蛋白质羰基（蛋白质氧化标志物）水平升高以及谷胱甘肽含量未改变证明了这一点。因此，该研究表明低水平微波辐射对认知功能有显著影响，并且还能够导致氧化应激。
