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模拟非对称人体肺气道中的分叉流动。

Modeling the bifurcating flow in an asymmetric human lung airway.

作者信息

Liu Y, So R M C, Zhang C H

机构信息

Department of Mechanical Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.

出版信息

J Biomech. 2003 Jul;36(7):951-9. doi: 10.1016/s0021-9290(03)00064-2.

Abstract

In a former paper, the inspiratory flow characteristics in a three-generation symmetric bifurcation airway have been numerically investigated using a control volume method to solve the fully three-dimensional laminar Navier-Stokes equations. The present paper extends the work to deal with asymmetric airway extracted from the 5th-11th branches of the model of Weibel (Morphometry of the Human Lung. New York Academic Press, Verlag, 1963) in order to more appropriately model human air passage. Computations are carried out in the Reynolds number range 200-1600, corresponding to mouth-air breathing rates ranging from 0.27 to 2.16l/s, representative for an averaged height man breathing from quiet to vigorous state. Particular attentions are paid to establishing relations between the Reynolds number and the overall flow characteristics, including flow patterns and pressure drop. The study shows that the ratios of airflow rate through the medial branches to that of their mother branches are the same, and this is also true for the ratios of airflow rate through the lateral branches. This partially explains why regular human breathing is not affected by airways of different sizes.

摘要

在之前的一篇论文中,使用控制体积法求解全三维层流纳维-斯托克斯方程,对三代对称分支气道中的吸气流动特性进行了数值研究。本文将工作扩展到处理从韦贝尔模型(《人类肺部形态学》。纽约学术出版社,1963年)的第5 - 11分支提取的不对称气道,以便更恰当地模拟人类气道。计算在雷诺数范围200 - 1600内进行,对应于口呼吸速率范围从0.27到2.16升/秒,代表平均身高的人从安静状态到剧烈状态呼吸的情况。特别关注建立雷诺数与整体流动特性之间的关系,包括流动模式和压降。研究表明,通过内侧分支的气流速率与其母分支气流速率的比值相同,通过外侧分支的气流速率比值也是如此。这部分解释了为什么正常人类呼吸不受不同大小气道的影响。

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