与自然杀伤细胞来源的大颗粒淋巴细胞增多症相关的蚊虫叮咬超敏反应：韩国的一例病例报告
Hypersensitivity to mosquito bites associated with natural killer cell-derived large granular lymphocyte lymphocytosis: a case report in Korea.
作者信息
Chung Joo Seop, Shin Ho Jin, Lee Eun Yup, Cho Goon Jae
机构信息
Department of Internal Medicine, Pusan National University College of Medicine, Busan, Korea.
出版信息
Korean J Intern Med. 2003 Mar;18(1):50-2. doi: 10.3904/kjim.2003.18.1.50.
Abstract
Hypersensitivity to mosquito bites (HMB) is characterized by intense skin reactions at bite sites. The pathogenesis of HMB might be related to clonal lymphoproliferation of Epstein-Barr virus DNA-positive natural killer (NK) cells. We report the first case of HMB possibly associated with NK cell-derived large granular lymphocyte (NK-LGL) lymphocytosis in Korea.
摘要
蚊虫叮咬超敏反应（HMB）的特征是叮咬部位出现强烈的皮肤反应。HMB的发病机制可能与爱泼斯坦-巴尔病毒DNA阳性自然杀伤（NK）细胞的克隆性淋巴细胞增殖有关。我们报告了韩国首例可能与NK细胞衍生的大颗粒淋巴细胞（NK-LGL）淋巴细胞增多症相关的HMB病例。
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