蚊虫叮咬过敏与 Epstein-Barr 病毒感染及自然杀伤细胞淋巴组织增生症相关 1 例

Department of Pediatrics, College of Medicine, Dankook University, Cheonan, Korea.

J Korean Med Sci. 2010 Feb;25(2):321-3. doi: 10.3346/jkms.2010.25.2.321. Epub 2010 Jan 25.

Hypersensitivity to mosquito bites (HMB) is a disorder characterized by a necrotic skin reaction and generalized symptoms subsequent to mosquito bites. It has been suggested that HMB is associated with chronic Epstein-Barr virus (EBV) infection and natural killer cell leukemia/lymphoma. We describe here a Korean child who had HMB associated with chronic EBV infection and natural killer cell lymphocytosis. A 5-yr-old boy was suffered from necrotic skin lesions on the right ear lobe. Type A EB virus was detected from hlood cells and bone marrow biospy recognized hemophagocyrosis.

对蚊子叮咬过敏（HMB）是一种以皮肤坏死性反应和蚊虫叮咬后全身症状为特征的疾病。有研究表明，HMB 与慢性 EBV（Epstein-Barr virus）感染和自然杀伤细胞白血病/淋巴瘤有关。我们在此描述了一例与慢性 EBV 感染和自然杀伤细胞淋巴组织增生相关的 HMB 韩国儿童病例。一名 5 岁男孩右耳垂出现坏死性皮肤损伤。从血液细胞和骨髓活检中检测到 A 型 EBV，并发现噬血细胞现象。