Rosan B
Infect Immun. 1976 Apr;13(4):1144-53. doi: 10.1128/iai.13.4.1144-1153.1976.
Previous studies indicated the a antigen was widely distributed among strains of Streptococcus sanguis and the group H streptococci. The cell walls of strains containing this antigen had moderate to large quantities of rhamnose, small amounts of phosphorus, and little to no ribitol. The molar ratios of the peptidoglycan amino acids and hexosamines suggested a di-alanyl cross bridge. The homogeneity of the walls of these strains suggested that serological group H can be considered synonymous with S. sanguis. In contrast those strains that did not contain the a antigen had only small amounts of rhamnose in their cell walls, galactosamine and ribitol were always detected, and large quantitites of phosphorus were present. The molar ratios of peptidoglycan components in the latter strains suggested a direct alanyl-lysl cross bridge. Although many of these strains had been classified either as S. sanguis or group H streptococci because of minor serological cross-reactions and similar biochemical properties, the distinct differences between the composition of their cell walls and those of S. sanguis and group H streptococci indicate that they do not belong in this species or group. The cell walls of strains containing the a antigen are relatively homogeneous and therefore it is suggested that cells containing this antigen be considered Lancefield serological group H.
以往的研究表明，a抗原广泛分布于血链球菌菌株和H群链球菌中。含有该抗原的菌株细胞壁含有适量至大量的鼠李糖、少量的磷，几乎不含或不含核糖醇。肽聚糖氨基酸和己糖胺的摩尔比表明存在二丙氨酰交联桥。这些菌株细胞壁的同质性表明血清学H群可被视为与血链球菌同义。相比之下，那些不含a抗原的菌株细胞壁中只有少量的鼠李糖，总是能检测到半乳糖胺和核糖醇，并且含有大量的磷。后一类菌株中肽聚糖成分的摩尔比表明存在直接的丙氨酰-赖氨酰交联桥。尽管其中许多菌株由于轻微的血清学交叉反应和相似的生化特性而被归类为血链球菌或H群链球菌，但它们细胞壁组成与血链球菌和H群链球菌之间的明显差异表明它们不属于这个种或群。含有a抗原的菌株细胞壁相对同质，因此建议将含有该抗原的细胞视为兰斯菲尔德血清学H群。
