血清III型血链球菌与兰斯菲尔德H群链球菌之间的血清学关系。

Serological relationships between serotype-III Streptococcus sanguis and Lancefield group-H streptococci.

作者信息

Akada H, Asakawa H, Kitamura K, Okahashi N, Koga T, Hamada S

出版信息

J Med Microbiol. 1987 Jun;23(4):321-6. doi: 10.1099/00222615-23-4-321.

Abstract

Certain strains of Streptococcus sanguis and group-H streptococci have been shown to have similar physiological properties and serological specificities. Serological studies revealed that serotype-III S. sanguis shared a common antigen with the so-called "British" group-H streptococci, but not with the "American" group-H streptococci. Serotype-III antigen was extracted in cold 5% trichloroacetic acid from isolated cell walls of S. sanguis ATCC 10558, and purified chromatographically. The purified serotype-III antigen consisted of neutral and amino sugars and some phosphorus, and was negatively charged. Hapten inhibition of the quantitative precipitin reaction between serotype-III antigen and antiserum indicated the strong possibility of alpha-glucosidic linkages being an immunodeterminant of the antigen.

摘要

已证明某些血链球菌菌株和H群链球菌具有相似的生理特性和血清学特异性。血清学研究表明，III型血链球菌与所谓的“英国”H群链球菌有共同抗原，但与“美国”H群链球菌没有。III型抗原是从血链球菌ATCC 10558分离的细胞壁中用冷5%三氯乙酸提取的，并通过色谱法纯化。纯化的III型抗原由中性糖、氨基糖和一些磷组成，带负电荷。III型抗原与抗血清之间定量沉淀反应的半抗原抑制表明，α-糖苷键很可能是该抗原的免疫决定簇。