Revankar Sanjay G
Dallas Veterans Affairs Medical Center, Texas, USA.
Am J Med Sci. 2003 May;325(5):262-74. doi: 10.1097/00000441-200305000-00003.
There has been considerable interest and concern in recent years regarding the potential health effects of mycotoxins in the indoor environment. Although the existence of mycotoxins has been known for several decades, relatively little is known about their effects in humans. What is known comes almost exclusively from studies of ingestion as the route of exposure. This review summarizes what is known regarding health effects of mycotoxins in general and specifically examines the evidence for the role of indoor exposure to the fungi of the genus Stachybotrys as a cause of disease in humans. Much work remains to be done in the area of mycotoxin research. The risk of health effects from ingestion seems much more widespread than from indoor airborne exposure, although the latter has received considerably more media attention. Rigorously controlled studies are needed to clarify these issues.
近年来，人们对室内环境中霉菌毒素的潜在健康影响产生了极大的兴趣并予以关注。尽管霉菌毒素的存在已为人所知数十年，但对于它们对人类的影响却知之甚少。已知的情况几乎完全来自于以摄入作为暴露途径的研究。本综述总结了关于霉菌毒素对健康影响的总体已知情况，并特别审视了室内接触葡萄穗霉属真菌作为人类疾病病因的证据。霉菌毒素研究领域仍有许多工作有待开展。摄入霉菌毒素对健康造成影响的风险似乎比室内空气传播暴露更为普遍，尽管后者受到了更多媒体关注。需要进行严格控制的研究来澄清这些问题。
