Dar-Odeh N S, Shehabi A A
Department of Oral Surgery, Oral Medicine, and Periodontics, University of Jordan, Amman, Jordan.
Mycoses. 2003 Jun;46(5-6):187-91. doi: 10.1046/j.1439-0507.2003.00871.x.
The prevalence of Candida species with and without denture-related stomatitis were evaluated in 167 Jordanian patients. The study revealed that 47 (28%) of the patients with denture-related stomatitis were colonized with Candida species (clinical group). Candida albicans was responsible for most cases of denture-related stomatitis (72%), and it was the only species capable of secreting aspartic proteinases. The study also indicated that candidal colonization was not influenced by predisposing haematological deficiencies, as both the clinical and control patient groups showed comparable haematological parameters and the differences were not significant (P > 0.05). All Candida species isolates were 100% susceptible to amphotericin B, while these isolates were less susceptible (25-75%) to fluconazole.
在167名约旦患者中评估了患和未患义齿性口炎的念珠菌属患病率。该研究显示，47名（28%）患义齿性口炎的患者被念珠菌属定植（临床组）。白色念珠菌是义齿性口炎大多数病例（72%）的病因，并且它是唯一能够分泌天冬氨酸蛋白酶的菌种。该研究还表明，念珠菌定植不受血液学易患缺陷的影响，因为临床组和对照组患者的血液学参数相当，差异不显著（P>0.05）。所有念珠菌属分离株对两性霉素B的敏感性均为100%，而这些分离株对氟康唑的敏感性较低（25%-75%）。
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