Banet-Noach Caroline, Malkinson Mertyn, Brill Assaf, Samina Isak, Yadin Hagai, Weisman Yoram, Pokamunski Shimon, King Roni, Deubel Vincent, Stram Yehuda
Kimron Veterinary Institute, Belt Dagan, Israel.
Virus Genes. 2003;26(2):135-41. doi: 10.1023/a:1023431328933.
In November 1997, an outbreak of a neuroparalytic disease caused by West Nile (WN) virus was diagnosed in young goose flocks. Domestic geese were similarly affected in the late summer and fall of 1998, 1999, 2000 and 2001. WN viruses were also isolated from migratory and wild birds and horses in 1998-2001. A 1278 bp sequence of the envelope gene of 24 Israeli WN virus isolates was compared with those of seven isolates from Africa, Europe and New York. As a result, the Israeli isolates could then be grouped into two clusters. The 15 avian and three equine from 1997-2001 in the first cluster of viruses were shown to be identical to WN-NY99, while the second cluster comprised one goose isolate from 1998 and two goose and two pigeon isolates from 2000. These closely resembled the most recent Old World isolates, and indicate that at least two WN genotypes were co-circulating in the region during this time.
1997年11月，在幼鹅群中诊断出由西尼罗河（WN）病毒引起的神经麻痹性疾病暴发。1998年、1999年、2000年和2001年的夏末和秋季，家鹅也受到类似影响。1998 - 2001年期间，还从候鸟、野鸟和马匹中分离出WN病毒。将24株以色列WN病毒分离株的包膜基因1278bp序列与来自非洲、欧洲和纽约的7株分离株的序列进行了比较。结果，以色列分离株可分为两个簇。第一簇病毒中1997 - 2001年的15株禽类和3株马类分离株与WN - NY99相同，而第二簇包括1998年的1株鹅分离株以及2000年的2株鹅分离株和2株鸽分离株。这些与最近的旧世界分离株极为相似，表明在此期间该地区至少有两种WN基因型在共同传播。
