Marcus Sheila M, Flynn Heather A, Blow Frederic C, Barry Kristen L
Department of Psychiatry, Women's Mood Disorders Program, University of Michigan Depression Center, University of Michigan Medical School, 900 Wall Street, Ann Arbor, MI 48109-0722, USA.
J Womens Health (Larchmt). 2003 May;12(4):373-80. doi: 10.1089/154099903765448880.
This study aimed to describe the prevalence of depressive symptomatology during pregnancy when seen in obstetric settings, the extent of treatment in this population, and specific risk factors associated with mood symptoms in pregnancy.
A total of 3472 pregnant women age 18 and older were screened while waiting for their prenatal care visits in 10 obstetrics clinics using a brief (10 minute) screening questionnaire. This screen measured demographics, tobacco and alcohol (TWEAK problem alcohol use screening measure), and depression measures, including the Center for Epidemiological Studies-Depression scale (CES-D), use of antidepressant medications, past history of depression, and current treatment (i.e., medications, psychotherapy, or counseling) for depression.
Of women screened, 20% (n = 689) scored above the cutoff score on the CES-D, and only 13.8% of those women reported receiving any formal treatment for depression. Past history of depression, poorer overall health, greater alcohol use consequences, smoking, being unmarried, unemployment, and lower educational attainment were significantly associated with symptoms of depression during pregnancy.
These data show that a substantial number of pregnant women screened in obstetrics settings have significant symptoms of depression, and most of them are not being monitored in treatment during this vulnerable time. This information may be used to justify and streamline systematic screening for depression in clinical encounters with pregnant women as a first step in determining which women may require further treatment for their mood symptoms. As elevations in depressive symptomatology have been associated with adverse maternal and infant outcomes, further study of the impact of psychiatric treatment in gravid women is essential.
本研究旨在描述在产科环境中就诊时孕期抑郁症状的患病率、该人群的治疗程度以及与孕期情绪症状相关的特定风险因素。
在10家产科诊所,对3472名18岁及以上的孕妇在等待产前检查时使用一份简短(10分钟)的筛查问卷进行筛查。该筛查测量了人口统计学特征、烟草和酒精使用情况(TWEAK问题饮酒筛查量表)以及抑郁测量指标,包括流行病学研究中心抑郁量表(CES-D)、抗抑郁药物的使用、抑郁病史以及当前针对抑郁的治疗(即药物治疗、心理治疗或咨询)。
在接受筛查的女性中,20%(n = 689)的CES-D得分高于临界值,而这些女性中只有13.8%报告接受过任何形式的抑郁治疗。抑郁病史、总体健康状况较差、饮酒后果更严重、吸烟、未婚、失业以及教育程度较低与孕期抑郁症状显著相关。
这些数据表明,在产科环境中接受筛查的大量孕妇有明显的抑郁症状,而且在这个脆弱时期,她们中的大多数没有接受治疗监测。这些信息可用于证明在与孕妇的临床接触中对抑郁进行系统筛查的合理性并简化流程,作为确定哪些女性可能需要针对其情绪症状进行进一步治疗的第一步。由于抑郁症状的加重与母婴不良结局相关,因此对妊娠期女性精神治疗影响的进一步研究至关重要。