Kwok A K H, Lai T Y Y
Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye Hospital, People's Republic of China.
Br J Ophthalmol. 2003 Jul;87(7):885-9. doi: 10.1136/bjo.87.7.885.
To determine the surgical outcome of indocyanine green (ICG) assisted retinal internal limiting membrane (ILM) peeling in macular hole surgery for severely myopic eyes and compare the visual and anatomical outcomes with an emmetropic control group.
10 severely myopic eyes (-6.0 D or greater) of 10 patients with macular holes without retinal detachment were recruited prospectively. All eyes received ICG assisted ILM removal of 3-4 disc diameters around the macular holes. Cases were matched with a prospective control group of 10 emmetropic macular hole patients who underwent identical ICG assisted ILM peeling surgery in the same period.
The mean refractive error in the myopic and control group was -11.8 D and +0.3 D, respectively (two tailed t test, p < 0.001). The mean follow up duration for the myopic and control group was 12.1 and 13.3 months, respectively (two tailed t test, p = 0.63). The primary anatomical closure rate in both groups was 90% (Fisher's exact test, p = 1.0). For both the myopic and control groups, there were significant improvement in the mean log MAR visual acuity after the surgery with improvements from 0.86 to 0.57 for the myopic group (two tailed t test, p = 0.015) and 0.89 to 0.44 for the control group (two tailed t test, p = 0.002). The mean preoperative and postoperative visual acuity, rates of final visual acuity of 20/50 or better, and improvement of two or more lines were not statistically different between the two groups.
ICG assisted ILM peeling in macular hole surgery for severely myopic eyes without retinal detachment gives promising anatomical and visual outcomes, which are comparable to that of non-severely myopic eyes.
确定吲哚菁绿（ICG）辅助视网膜内界膜（ILM）剥除术在高度近视眼黄斑裂孔手术中的手术效果，并将视力和解剖学结果与正视对照组进行比较。
前瞻性招募10例黄斑裂孔且无视网膜脱离的高度近视患者的10只眼（-6.0 D或更高）。所有眼睛均接受ICG辅助的黄斑裂孔周围3 - 4个视盘直径范围的ILM切除。病例与同期进行相同ICG辅助ILM剥除手术的10例正视黄斑裂孔患者的前瞻性对照组进行匹配。
近视组和对照组的平均屈光不正分别为-11.8 D和+0.3 D（双侧t检验，p < 0.001）。近视组和对照组的平均随访时间分别为12.1个月和13.3个月（双侧t检验，p = 0.63）。两组的主要解剖学闭合率均为90%（Fisher精确检验，p = 1.0）。对于近视组和对照组，术后平均log MAR视力均有显著改善，近视组从0.86提高到0.57（双侧t检验，p = 0.015），对照组从0.89提高到0.44（双侧t检验，p = 0.002）。两组术前和术后的平均视力、最终视力达到20/50或更好的比例以及提高两行或更多行的比例在统计学上无差异。
ICG辅助ILM剥除术用于无视网膜脱离的高度近视眼黄斑裂孔手术可获得良好的解剖学和视力结果，与非高度近视眼相当。
