Wolf S, Reichel M B, Wiedemann P, Schnurrbusch U E K
Klinik und Poliklinik für Augenheilkunde, Liebigstrasse 10-14, 04103 , Leipzig, Germany.
Graefes Arch Clin Exp Ophthalmol. 2003 Jul;241(7):589-592. doi: 10.1007/s00417-003-0673-1. Epub 2003 May 8.
Indocyanine green (ICG) staining of the internal limiting membrane has facilitated ILM peeling in macular hole surgery. However, it has been reported that ICG-assisted peeling of the ILM may result in retinal damage and unfavorable functional outcome. Therefore, we analyzed our visual and anatomical results of ICG assisted macular hole surgery.
In a retrospective study the records of a consecutive series of 37 patients with full-thickness idiopathic macular holes operated with ICG-assisted ILM peeling by a single surgeon were analyzed. All patients underwent a standard three-port vitrectomy with surgically induced posterior vitreous detachment, staining of the ILM with ICG, peeling of the ILM in a circular manner around the fovea, and SF6 20% endotamponade.
A total of 37 patients (37 eyes) were included in the study. The mean age was 69+/-7 years (range 52-81 years), and there were 26 women and 11 men. The follow-up ranged from 6 to 30 months (mean 18+/-6 months). At baseline visual acuity ranged from 20/400 to 20/40. Anatomically, 13 eyes had stage 2 holes, 21 eyes (57%) stage 3 holes, and three eyes stage 4 holes. At the postoperative visit (8-12 weeks after surgery) anatomical closure of the macular hole was achieved in 36 eyes. Visual acuity ranged between 20/400 and 20/20. At the last follow-up after initial surgery the macular hole was closed in all eyes. Visual acuity ranged from 20/200 to 20/20.
In our retrospective series anatomical and functional results of macular hole surgery with ICG-assisted peeling of the ILM are satisfactory. Primary hole closure was achieved in 97% of eyes and visual acuity increased in 62% of eyes in our series.
内界膜的吲哚菁绿（ICG）染色有助于黄斑裂孔手术中的内界膜剥除。然而，有报道称ICG辅助的内界膜剥除可能导致视网膜损伤和不良的功能预后。因此，我们分析了ICG辅助黄斑裂孔手术的视觉和解剖学结果。
在一项回顾性研究中，分析了由一名外科医生采用ICG辅助内界膜剥除术连续治疗的37例特发性全层黄斑裂孔患者的记录。所有患者均接受标准的三通道玻璃体切除术，包括手术诱导的玻璃体后脱离、用ICG对内界膜进行染色、围绕黄斑中心凹环形剥除内界膜以及20%的六氟化硫气体眼内填充。
本研究共纳入37例患者（37只眼）。平均年龄为69±7岁（范围52 - 81岁），其中女性26例，男性11例。随访时间为6至30个月（平均18±6个月）。基线视力范围为20/400至20/40。解剖学上，13只眼为2期裂孔，21只眼（57%）为3期裂孔，3只眼为4期裂孔。术后随访（手术后8 - 12周）时，36只眼黄斑裂孔实现了解剖学闭合。视力范围在20/400至20/20之间。在初次手术后的最后一次随访时，所有眼的黄斑裂孔均已闭合。视力范围为20/200至20/20。
在我们的回顾性系列研究中，ICG辅助内界膜剥除的黄斑裂孔手术的解剖学和功能结果令人满意。在我们的系列研究中，97%的眼实现了原发性裂孔闭合，62%的眼视力提高。
