Kantor David B, Kolodkin Alex L
Department of Neuroscience, The Johns Hopkins School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.
Neuron. 2003 Jun 19;38(6):849-52. doi: 10.1016/s0896-6273(03)00364-7.
The embryonic nervous system is refined over the course of development as a result of the twin processes of naturally occurring cell death and selective axon pruning. Recent studies provide new insights into the molecular events that underlie axon pruning and underscore the diversity of refinement processes employed by the nervous system during development.
在发育过程中，由于自然发生的细胞死亡和选择性轴突修剪这两个过程，胚胎神经系统得以完善。最近的研究为轴突修剪背后的分子事件提供了新的见解，并强调了神经系统在发育过程中所采用的完善过程的多样性。
