Abensur H, Romäo Júnior J E, Prado E B, Kakehashi E T, Sabbaga E, Marcondes M
Hospital Das Clinicas, São Paulo University, Brazil.
Adv Perit Dial. 1992;8:3-6.
Peritoneal lymphatic absorption rate (LAR) in 15 patients on a CAPD program was measured by estimation of the disappearance of dextran 70 from the peritoneal cavity. The LAR was 1.03 +/- 0.45 ml/min. The cumulative lymphatic absorption, cumulative net transcapillary ultrafiltration, calculated net ultrafiltration (CUF) and measured net ultrafiltration (MUF) at 4 h exchange were respectively: 261 +/- 127 ml, 694 +/- 134 ml, 446 +/- 135 ml and 409 +/- 136 ml. Calculated and measured net ultrafiltration didn't differ significantly. An inverse correlation between MUF and LAR and a positive correlation between MUF and the ratio for dialysate glucose concentration at 4 hand dialysate glucose at 0 h (G4/G0) were observed (r = -0.522 and 0.547, respectively, p < 0.05). The multiple correlation coefficient between the MUF and LAR plus G4/G0 was higher (r = 0.617, p < 0.05). Peritonitis and the presence of diabetes didn't interfere with LAR. We have concluded that lymphatic absorption plus peritoneal transfer rate of glucose are important determinants of intraperitoneal volumes and that dextran 70 is a useful marker to measure lymphatic absorption.
通过评估右旋糖酐70从腹腔内的消失情况，对15名接受持续性非卧床腹膜透析（CAPD）治疗的患者的腹膜淋巴吸收率（LAR）进行了测量。LAR为1.03±0.45毫升/分钟。4小时交换时的累积淋巴吸收量、累积净跨毛细血管超滤量、计算得出的净超滤量（CUF）和测量得出的净超滤量（MUF）分别为：261±127毫升、694±134毫升、446±135毫升和409±136毫升。计算得出的净超滤量和测量得出的净超滤量无显著差异。观察到MUF与LAR之间呈负相关，MUF与4小时透析液葡萄糖浓度与0小时透析液葡萄糖浓度之比（G4/G0）之间呈正相关（r分别为-0.522和0.547，p<0.05）。MUF与LAR加G4/G0之间的复相关系数更高（r=0.617，p<0.05）。腹膜炎和糖尿病的存在并未干扰LAR。我们得出结论，淋巴吸收加上葡萄糖的腹膜转运率是腹腔内液体量的重要决定因素，并且右旋糖酐70是测量淋巴吸收的有用标志物。
