平山病患者颈部前屈时的颈髓功能障碍。
Cervical cord dysfunction during neck flexion in Hirayama's disease.
作者信息
Restuccia D, Rubino M, Valeriani M, Mirabella M, Sabatelli M, Tonali P
机构信息
Department of Neurology, Catholic University, Rome, Italy.
出版信息
Neurology. 2003 Jun 24;60(12):1980-3. doi: 10.1212/01.wnl.0000068017.75780.44.
Neck flexion may play a role in the pathogenesis of Hirayama disease. Upper limb somatosensory evoked potentials were recorded in five patients with Hirayama disease, six patients with ALS, and 14 healthy subjects. Neck flexion caused a significant amplitude decrease of the N13 cervical response only in patients with Hirayama disease. Direct cord compression or microvascular changes can in theory account for this position-related dysfunction.
颈部前屈可能在平山病的发病机制中起作用。对5例平山病患者、6例肌萎缩侧索硬化症患者和14名健康受试者记录了上肢体感诱发电位。仅在平山病患者中，颈部前屈导致N13颈部反应的波幅显著降低。理论上，脊髓直接受压或微血管变化可解释这种与姿势相关的功能障碍。
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