Adachi Hayamitsu, Nishimura Yoshio
Institute of Microbial Chemistry, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021, Japan.
Nat Prod Res. 2003 Aug;17(4):253-7. doi: 10.1080/1057563021000060112.
Bactobolin glucosides, 5-O-(alpha-D-glucopyranosyl)-, 5-O-(beta-D-glucopyranosyl)- and 6-O-(beta-D-glucopyranosyl)-bactobolin were prepared by glycosidation of bactobolin (1) with the glucopyranosyl trichloroacetoimidate. These compounds were evaluated antimicrobial activity and cytotoxicity.
通过将杆菌生素（1）与吡喃葡萄糖基三氯乙酰亚胺酯进行糖苷化反应，制备了5-O-（α-D-吡喃葡萄糖基）-、5-O-（β-D-吡喃葡萄糖基）-和6-O-（β-D-吡喃葡萄糖基）-杆菌生素葡萄糖苷。对这些化合物的抗菌活性和细胞毒性进行了评估。
