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Regeneration of an adult peripheral nerve preparation in culture.

作者信息

Kanje M

机构信息

Department of Animal Physiology, University of Lund, Sweden.

出版信息

Mol Neurobiol. 1992 Summer-Fall;6(2-3):217-23. doi: 10.1007/BF02780554.

DOI:10.1007/BF02780554
PMID:1282333
Abstract

The methods used to maintain the vagus nerve from the adult rat in culture and how regeneration is studied in this preparation are described. A hypothesis is presented on the triggering of the cell body reaction. It is suggested that this reaction is initiated by proteins synthesized in nonneuronal cells at the site of a nerve lesion. These proteins, referred to as regenerins, reach the nerve cell body by retrograde axonal transport, where they initiate the regeneration process.

摘要

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本文引用的文献

1
Regeneration in vitro of the adult frog sciatic sensory axons.体外培养成年蛙坐骨感觉轴突的再生。
Restor Neurol Neurosci. 1990 Jan 1;1(3):261-6. doi: 10.3233/RNN-1990-13413.
2
Growth-associated proteins and the curious dichotomies of nerve regeneration.生长相关蛋白与神经再生的奇妙二分法
Cell. 1984 Jul;37(3):697-700. doi: 10.1016/0092-8674(84)90404-5.
3
Denervated sheath cells secrete a new protein after nerve injury.去神经支配的鞘细胞在神经损伤后分泌一种新蛋白质。
Proc Natl Acad Sci U S A. 1983 Jul;80(13):4169-73. doi: 10.1073/pnas.80.13.4169.
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Axonally transported proteins associated with axon growth in rabbit central and peripheral nervous systems.与兔中枢和外周神经系统轴突生长相关的轴突运输蛋白。
J Cell Biol. 1981 Apr;89(1):96-103. doi: 10.1083/jcb.89.1.96.
5
The axon reaction: a review of the principal features of perikaryal responses to axon injury.轴突反应:对轴突损伤后胞体反应主要特征的综述
Int Rev Neurobiol. 1971;14:49-124. doi: 10.1016/s0074-7742(08)60183-x.
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What is the signal for chromatolysis?染色质溶解的信号是什么?
Brain Res. 1970 Sep 29;23(1):1-21. doi: 10.1016/0006-8993(70)90345-8.
7
Ornithine decarboxylase in motoneurons during regeneration.再生过程中运动神经元中的鸟氨酸脱羧酶
Exp Neurol. 1985 Sep;89(3):679-88. doi: 10.1016/0014-4886(85)90016-0.
8
Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve.白细胞介素-1调节大鼠坐骨神经非神经元细胞中神经生长因子的合成。
Nature. 1987;330(6149):658-9. doi: 10.1038/330658a0.
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Regeneration in vitro of the adult frog sciatic nerve.成年青蛙坐骨神经的体外再生
Neurosci Lett. 1988 Jul 19;90(1-2):113-8. doi: 10.1016/0304-3940(88)90796-3.
10
Changes in neurofilament gene expression occur after axotomy of dorsal root ganglion neurons: an in situ hybridization study.背根神经节神经元轴突切断后神经丝基因表达的变化:一项原位杂交研究。
Metab Brain Dis. 1987 Dec;2(4):291-303. doi: 10.1007/BF00999699.