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[达里埃病的离心性环状红斑。外用骨化三醇和311纳米窄谱中波紫外线光疗的成功治疗]

[Erythema annulare centrifugum Darier. Successful therapy with topical calcitriol and 311 nm-ultraviolet B narrow band phototherapy].

作者信息

Reuter J, Braun-Falco M, Termeer C, Bruckner-Tuderman L

机构信息

Universitäts-Hautklinik, Hauptstrasse 7, 79104 Freiburg.

出版信息

Hautarzt. 2007 Feb;58(2):146-8. doi: 10.1007/s00105-006-1131-x.

Abstract

Erythema annulare centrifugum is an acute dermatosis of unclear etiology, which presents with annular erythematous lesions with marginal scale. Therapeutically, systemic and topical glucocorticosteroids are used primarily. We treated a patient with large lesions in the area of the thighs resistant to a therapy with topical glucocorticosteroids, with topical calcitriol in combination with 311 nm ultraviolet B narrow band phototherapy. After four weeks of treatment the skin lesions had cleared nearly completely without any side effects. The combination topical vitamin D3-analogue calcitriol and 311 nm ultraviolet B narrow band phototherapy was effective and can be regarded as a useful alternative to glucocorticosteroids for erythema annulare centrifugum.

摘要

离心性环状红斑是一种病因不明的急性皮肤病,表现为边缘有鳞屑的环状红斑性损害。治疗上主要使用全身性和局部糖皮质激素。我们治疗了一名大腿部位有大片皮损且对局部糖皮质激素治疗耐药的患者,采用局部骨化三醇联合311纳米窄谱中波紫外线光疗。治疗四周后,皮肤损害几乎完全消退,且无任何副作用。局部维生素D3类似物骨化三醇与311纳米窄谱中波紫外线光疗联合使用有效,可被视为离心性环状红斑治疗中糖皮质激素的一种有效替代方法。

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