Kim Dai-Jin, Yoon Su-Jung, Lee Heung-Pyo, Choi Bo-Moon, Go Hyo Jin
Department of Psychiatry, College of Medicine, Catholic University of Korea, Buchon City, Kyunggi Do, Korea.
Int J Neurosci. 2003 Apr;113(4):581-94. doi: 10.1080/00207450390162308.
A hangover is characterized by the constellation of unpleasant physical and mental symptoms that occur between 8 and 16 h after drinking alcohol. We evaluated the effects of experimentally-induced alcohol hangover on cognitive functions using the Luria-Nebraska Neuropsychological Battery. A total of 13 normal adult males participated in this study. They did not have any previous histories of psychiatric or medical disorders. We defined the experimentally-induced hangover condition at 13 h after drinking a high dose of alcohol (1.5 g/kg of body weight). We evaluated the changes of cognitive functions before drinking alcohol and during experimentally-induced hangover state. The Luria-Nebraska Neuropsychological Battery was administrated in order to examine the changes of cognitive functions. Cognitive functions, such as visual, memory, and intellectual process functions, were decreased during the hangover state. Among summary scales, the profile elevation scale was also increased. Among localization scales, the scores of left frontal, sensorimotor, parietal-occipital dysfunction, and right parietal-occipital scales were increased during the hangover state. These results indicate that alcohol hangovers have a negative effect on cognitive functions, particularly on the higher cortical and visual functions associated with the left hemisphere and right posterior hemisphere.
宿醉的特征是在饮酒后8至16小时出现一系列令人不适的身心症状。我们使用鲁利亚-内布拉斯加神经心理成套测验评估了实验诱导的酒精性宿醉对认知功能的影响。共有13名正常成年男性参与了本研究。他们既往没有任何精神或医学疾病史。我们将饮用高剂量酒精（1.5克/千克体重）13小时后定义为实验诱导的宿醉状态。我们评估了饮酒前和实验诱导的宿醉状态期间认知功能的变化。为了检查认知功能的变化，实施了鲁利亚-内布拉斯加神经心理成套测验。在宿醉状态期间，视觉、记忆和智力过程功能等认知功能下降。在综合量表中，剖面图升高量表也升高。在定位量表中，左额叶、感觉运动、顶枕功能障碍和右顶枕量表的分数在宿醉状态期间升高。这些结果表明，酒精性宿醉对认知功能有负面影响，尤其是对与左半球和右后半球相关的高级皮质和视觉功能。
