Belkoff Stephen M, Molloy Sean
Orthopaedic Instrumentation Laboratory, Department of Orthopaedic Surgery, Johns Hopkins University/Johns Hopkins Bayview Medical Center, Baltimore, Maryland 21224-2780, USA.
Spine (Phila Pa 1976). 2003 Jul 15;28(14):1555-9.
Ex vivo biomechanical study using osteoporotic cadaveric vertebral bodies.
To measure internal vertebral body temperature during polymerization of cements used for vertebroplasty.
Previous ex vivo studies have shown that temperature increases during cement polymerization were unlikely to cause thermal necrosis.
Twenty-four osteoporotic vertebral bodies were instrumented with thermocouples and injected with one of two cement volumes (6 or 10 mL) of one of two cements (Simplex P or modified Simplex P, Stryker-Howmedica-Osteonics, Kalamazoo, MI). Vertebral bodies were placed in a bath (37 C) and temperatures were measured for 15 minutes from the time the cement was initially mixed.
In the vertebral bodies, peak temperatures at the anterior cortex ranged from 44 C to 113 C, those in the center ranged from 49 C to 112 C, and those at the spinal canal ranged from 39 C to 57 C. Dwell times at temperatures above 50 C at the anterior cortex ranged from 0 to 5.5 minutes, those in the center ranged from 0 to 8 minutes, and those at the spinal canal ranged from 0 to 2.5 minutes.
Internal temperature elevation measured during cement polymerization was substantially higher than previously reported and may be sufficiently high to pose a risk of thermal necrosis.
使用骨质疏松症尸体椎体进行体外生物力学研究。
测量椎体成形术中所用骨水泥聚合过程中椎体内部的温度。
先前的体外研究表明，骨水泥聚合过程中的温度升高不太可能导致热坏死。
对24个骨质疏松症椎体安装热电偶，并注入两种骨水泥（Simplex P或改良Simplex P，史赛克-豪美迪克-奥施康定公司，密歇根州卡拉马祖）之一的两种骨水泥体积（6或10毫升）中的一种。将椎体置于水浴（37℃）中，从骨水泥最初混合之时起测量温度15分钟。
在椎体中，前皮质的峰值温度范围为44℃至113℃，中心的峰值温度范围为49℃至112℃，椎管处的峰值温度范围为39℃至57℃。前皮质温度高于50℃的停留时间范围为0至5.5分钟，中心为0至8分钟，椎管处为0至2.5分钟。
骨水泥聚合过程中测得的内部温度升高显著高于先前报道，可能高到足以构成热坏死风险。
