Yue Weihua, Hao Wei, Liu Pozi, Liu Tieqiao, Ni Ming, Guo Qi
Mental Health Institute, Second Xiangya Hospital, Central South University, 86, Middle Renmin Road, 410011, Changsha, Hunan, People's Republic of China.
Can J Psychiatry. 2003 Jun;48(5):318-23. doi: 10.1177/070674370304800507.
To investigate the psychological status of patients with sleep apnea-hypopnea syndrome (SAHS) and to evaluate the association of SAHS with psychological symptoms, using the Symptom Checklist-90 (SCL-90) scale.
The study comprised 30 SAHS patients (25 men, 5 women) and 30 matched, healthy control subjects. They all completed the SCL-90 and the Epworth Sleep Scale (ESS) and underwent a whole-night polysomnographic (PSG) examination. We used t-tests for group comparisons of nocturnal PSG characteristics, daytime sleepiness, and psychological symptoms. We employed Spearman's rank correlation analysis to indicate the effects of several nocturnal PSG variables (for example, total sleep time, percentage of wake at sleep, Apnea and Hypopnea Index [AHI], and oxygen desaturation) or subjective daytime sleepiness on psychological symptoms in SAHS.
SAHS patients suffered from fragmented sleep and decreased arterial oxygen saturations, compared with healthy control subjects. The General Severity Index (GSI) of SCL-90 was significantly higher in SAHS patients than in healthy control subjects, as were measures of somatization, obsession-compulsion, depression, anxiety, and hostility (P < 0.05). The severity of psychological symptoms in SAHS patients was negatively related to total sleep time and percentage of stage 2 nonrapid eye movement (NREM) sleep; it was positively related to percentage of wake time after sleep onset, percentage of stage 1 NREM sleep, and ESS scores.
In our study population, SAHS patients had decreased psychological well-being, which could be explained by fragmented sleep or excessive daytime sleepiness.
使用症状自评量表90（SCL - 90）评估睡眠呼吸暂停低通气综合征（SAHS）患者的心理状态，并评估SAHS与心理症状之间的关联。
本研究纳入30例SAHS患者（25例男性，5例女性）和30例匹配的健康对照者。他们均完成SCL - 90和爱泼沃斯思睡量表（ESS），并接受整夜多导睡眠图（PSG）检查。我们使用t检验对夜间PSG特征、日间嗜睡和心理症状进行组间比较。采用Spearman等级相关分析来表明几个夜间PSG变量（例如，总睡眠时间、睡眠中觉醒百分比、呼吸暂停低通气指数[AHI]和氧饱和度下降）或主观日间嗜睡对SAHS患者心理症状的影响。
与健康对照者相比，SAHS患者睡眠碎片化，动脉血氧饱和度降低。SAHS患者的SCL - 90总体严重程度指数（GSI）显著高于健康对照者，躯体化、强迫、抑郁、焦虑和敌对性的测量指标也是如此（P < 0.05）。SAHS患者心理症状的严重程度与总睡眠时间和非快速眼动（NREM）睡眠2期百分比呈负相关；与睡眠开始后觉醒时间百分比、NREM睡眠1期百分比和ESS评分呈正相关。
在我们的研究人群中，SAHS患者心理健康状况下降，这可能由睡眠碎片化或日间过度嗜睡所解释。
